ArticleCurrent behavioral neuroscience reports2018
Review of Neurobiological Influences on Externalizing and Internalizing Pathways to Alcohol Use Disorder.
Article in Current behavioral neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed.
- Neurobiological subtypes in alcohol use disorder and their phenotypic and clinical profiles.Molecular psychiatry · 2026Article
- Subjective response to alcohol predicts motivation to self-administer alcohol in a progressive ratio task.Experimental and clinical psychopharmacology · 2025Article
- Correlational and causal modeling of alcohol-related symptoms and internalizing disorder status: Further elucidation of a harm paradox.Alcohol, clinical & experimental research · 2025Article
- Functional Brain Connectivity Predictors of Prospective Substance Use Initiation and Their Environmental Correlates.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Functional brain connectivity predictors of prospective substance use initiation and their environmental correlates.medRxiv : the preprint server for health sciences · 2024Article
- Neuroendocrine mechanisms in the links between early life stress, affect, and youth substance use: A conceptual model for the study of sex and gender differences.Frontiers in neuroendocrinology · 2024Review
- Neural correlates of negative life events and their relationships with alcohol and cannabis use initiation.Dialogues in clinical neuroscience · 2023Article
- Associations between specific sleep and circadian characteristics and alcohol use disorder criteria and problems.Addictive behaviors · 2022Article
- Multidimensional Quality of Life Across the Spectrum of Alcohol Use Behavior.Psychiatric research and clinical practice · 2022Article
- The externalizing and internalizing pathways to marijuana use initiation: Examining the synergistic effects of impulsiveness and sensation seeking.Developmental psychology · 2021Article
- Cold-Blooded and on Purpose: A Review of the Biology of Proactive Aggression.Brain sciences · 2021Review
- The associations of comorbid substance use disorders and psychiatric conditions with adolescent brain structure and function: A review.Journal of the neurological sciences · 2020Review
- Alcohol expectancies mediate the association between the neural response to emotional words and alcohol consumption.Drug and alcohol dependence · 2020Article
- Neuromodulation of brain activation associated with addiction: A review of real-time fMRI neurofeedback studies.NeuroImage. Clinical · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
purpose of reviewTwo developmental courses through which alcohol use disorder (AUD) may emerge include externalizing and internalizing pathways. We review recent neuroimaging studies of potential neural risk factors for AUD and link findings to potential behavioral risk factors for AUD. RECENT
findingsThere is evidence that early-emerging weakness in prefrontal functioning and later-emerging differences in reward-system functioning contribute to an externalizing risk pathway. Stress may be an important contributor in the internalizing pathway through a blunting of reward-related activation, which may act alone or in combination with heightened emotion-related reactivity. SUMMARY: This review highlights areas for future work, including investigation of the relative balance between prefrontal and subcortical circuitry, attention to stages of AUD, and consideration of environmental factors such as stress and sleep. Particularly important is longitudinal work to understand the temporal ordering of associations among brain maturation, behavioral risk, and alcohol use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.