ArticleNature neuroscience2019
Unsupervised identification of the internal states that shape natural behavior.
Article in Nature neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 129 papers.
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Who cites it
129 citing papers in PubMed.
- Decoding behavior with minimal and interpretable agent models.PLoS computational biology · 2026Article
- Inferring the causes of noise from binary outcomes: A normative theory of learning under uncertainty.Psychological review · 2026Article
- Canonical decision computations underlie behavioral and neural signatures of cooperation in primates.Neuron · 2026Article
- Uncovering internal states with a robust shared-state multi-neuron GLM-HMM framework.bioRxiv : the preprint server for biology · 2026Article
- Striatal dopamine signals internal states related to behavioral performance over prolonged timescales in monkeys.bioRxiv : the preprint server for biology · 2026Article
- Compositionality of social gaze in the prefrontal-amygdala circuits.Nature communications · 2026Article
- Primary cilia and neural computation.Journal of biomedical science · 2026Review
- Diurnal rhythms of choice: a novel state-dependent drift diffusion model uncovers time-dependent changes in rat decision making.Research square · 2026Article
- Diurnal rhythms of choice: a novel state-dependent drift diffusion model uncovers time-dependent changes in rat decision making.bioRxiv : the preprint server for biology · 2026Article
- Sex-specific behavioral feedback modulates sensorimotor processing and drives flexible social behavior.Nature communications · 2026Article
- Cerebellar acceleration of learning in an evidence-accumulation task.Cell reports · 2026Article
- Article
- Sharing the spotlight: Uncovering common attentional dynamics across species.PLoS computational biology · 2026Article
- Primate neuroethology: a new synthesis.Trends in cognitive sciences · 2026Review
- Recent social experience alters song behavior in Drosophila.Current biology : CB · 2026Article
- Neuromodulators Generate Multiple Context-Relevant Behaviors in Recurrent Neural Networks.Neural computation · 2026Article
- Understanding the Brain as a Mentalizing Machine with a Symbol Grounding Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Infinite hidden Markov models can dissect the complexities of learning.Nature neuroscience · 2026Article
- JOINT MODELING FOR LEARNING DECISION-MAKING DYNAMICS IN BEHAVIORAL EXPERIMENTS.The annals of applied statistics · 2025Article
- Article
69 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Internal states shape stimulus responses and decision-making, but we lack methods to identify them. To address this gap, we developed an unsupervised method to identify internal states from behavioral data and applied it to a dynamic social interaction. During courtship, Drosophila melanogaster males pattern their songs using feedback cues from their partner. Our model uncovers three latent states underlying this behavior and is able to predict moment-to-moment variation in song-patterning decisions. These states correspond to different sensorimotor strategies, each of which is characterized by different mappings from feedback cues to song modes. We show that a pair of neurons previously thought to be command neurons for song production are sufficient to drive switching between states. Our results reveal how animals compose behavior from previously unidentified internal states, which is a necessary step for quantitative descriptions of animal behavior that link environmental cues, internal needs, neuronal activity and motor outputs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.