ArticleNature neuroscience2019
Affective memory rehearsal with temporal sequences in amygdala neurons.
Article in Nature neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Article
- Fear learning induces synaptic potentiation between engram neurons in the rat lateral amygdala.Nature neuroscience · 2024Article
- Article
- Targeting Histamine and Histamine Receptors for Memory Regulation: An Emotional Perspective.Current neuropharmacology · 2024Review
- Article
- Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Average reward rates enable motivational transfer across independent reinforcement learning tasks.Frontiers in behavioral neuroscience · 2022Article
- Neuronal Sequence Models for Bayesian Online Inference.Frontiers in artificial intelligence · 2021Review
- Multidimensional processing in the amygdala.Nature reviews. Neuroscience · 2020Review
- Pavlovian patterns in the amygdala.Nature neuroscience · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Affective learning and memory are essential for daily behavior, with both adaptive and maladaptive learning depending on stimulus-evoked activity in the amygdala circuitry. Behavioral studies further suggest that post-association offline processing contributes to memory formation. Here we investigated spike sequences across simultaneously recorded neurons while monkeys learned to discriminate between aversive and pleasant tone-odor associations. We show that triplets of neurons exhibit consistent temporal sequences of spiking activity that differed from firing patterns of individual neurons and pairwise correlations. These sequences occurred throughout the long post-trial period, contained valence-related information, declined as learning progressed and were selectively present in activity evoked by the recent pairing of a conditioned stimulus with an unconditioned stimulus. Our findings reveal that temporal sequences across neurons in the primate amygdala serve as a coding mechanism and might aid memory formation through the rehearsal of the recently experienced association.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.