Evidence map›Paper›PMID 31768035›Full record

ArticleNature chemical biology2020

Engineering a nicotinamide mononucleotide redox cofactor system for biocatalysis.

William B Black, Linyue Zhang, Wai Shun Mak, Sarah Maxel, Youtian Cui, Edward King, Bonnie Fong, Alicia Sanchez Martinez, Justin B Siegel, Han Li

Open access · greenAbstract read
In one paragraph

Article in Nature chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 123 citations in OpenAlex.

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  17. Orthogonal redox control.Nature chemical biology · 2024
    Article
  18. Article
  19. EngineeringACS catalysis · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

William B Black *Department of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, CA, USA.
Linyue Zhang *Department of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, CA, USA.
Wai Shun Mak *Department of Chemistry, University of California, Davis, Davis, CA, USA.
Sarah MaxelDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, CA, USA.
Youtian CuiDepartment of Chemistry, University of California, Davis, Davis, CA, USA.
Edward KingDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, USA.
Bonnie FongDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, CA, USA.
Alicia Sanchez MartinezDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, CA, USA.
Justin B SiegelDepartment of Chemistry, University of California, Davis, Davis, CA, USA. jbsiegel@ucdavis.edu.
Han LiDepartment of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, CA, USA. han.li@uci.edu.ORCID http://orcid.org/0000-0002-6113-6433
University of California, Irvine · USUniversity of California, Davis · US

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAJ, FAWAZ GEORGE · 1987 to 2021
$50.1M
Enzymatic formation of the hydrocarbon skeletons underlying diterpenoid diversityR01GM076324 · NIGMS · IOWA STATE UNIVERSITY · PI PETERS, REUBEN JOHN · 2006 to 2019
$3.4M
Engineering an unnatural redox cofactor (uRedox) system for efficient biosynthesis of medicinesDP2GM137427 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LI, HAN · 2019 to 2022
$2.4M
NIEHS NIH HHS P42 ES004699NIGMS NIH HHS DP2 GM137427NIGMS NIH HHS R01 GM076324
6 · The paper itself

Abstract

Biological production of chemicals often requires the use of cellular cofactors, such as nicotinamide adenine dinucleotide phosphate (NADP

Indexed as

Oxidation-ReductionBiocatalysisCarbonChromatography, GasCyclohexanonesEscherichia coliKineticsNADNADPNicotinamide MononucleotideProtein ConformationProtein EngineeringPseudomonas putidaRalstoniaSoftwareCarbonCyclohexanoneslevodioneNADNADPNicotinamide Mononucleotide

Identifiers

PMID31768035
PMCPMC7546441
OpenAlexW2989621922

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.