ArticleNature microbiology2020
The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon.
Open access · greenAbstract read
In one paragraph
Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.
0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
95 citing papers in PubMed, 134 citations in OpenAlex.
- Induction of DNA-mediated immune responses by bacterial extracellular vesicles results in control of murine norovirus infection.Gut microbes · 2026Article
- Gut microbiome-enteric virus interactions: mechanisms, clinical implications, and translational directions.Journal of gastroenterology · 2026Review
- Plscr1 inhibits murine norovirus entry.bioRxiv : the preprint server for biology · 2026Article
- Gut microbe-derived short-chain fatty acids regulate alphavirus arthritis and macrophage activation in mice.The Journal of clinical investigation · 2026Article
- Specific bile acids can elicit the type-I interferon response through the cGAS-STING pathway.Cell communication and signaling : CCS · 2026Article
- STAT1 expression in myeloid cells restrains murine norovirus-induced hepatitis and fibrosis.bioRxiv : the preprint server for biology · 2026Article
- Spatially and temporally comparative proteomics provide insights into dynamic response patterns to PEDV infection.Communications biology · 2026Article
- Ursodeoxycholic acid inhibits pneumonia caused by PRCV through the activation of TLR4-IRF3 mediated type Ⅰ interferon pathway.Veterinary research · 2026Article
- Host-microbial co-metabolites: from biogenesis to immunomodulation and implications for health and disease.Frontiers in immunology · 2026Review
- Effects of bacteriophages on gut microbiome functionality.Gut microbes · 2025Review
- Host-specific bacterial modulation of airway gene expression and alternative splicing.mSphere · 2025Article
- Article
- The Role of the Microbiome in the Resolution of Infection-Induced Inflammation.ACS infectious diseases · 2025Review
- CVID Enteropathy Associated With Chronic Norovirus Infection: Background, Clinical Features, and Therapeutic Aspects.Reviews in medical virology · 2025Review
- Article
- Determining the Importance of Carbohydrate-Based Structures in Murine Norovirus Binding to Commensal Bacteria.Viruses · 2025Article
- A novel therapy targeting the gut-liver axis for chronic hepatitis B: Ursodeoxycholic acid plusJHEP reports : innovation in hepatology · 2025Article
- Trim7 does not have a role in the restriction of murine norovirus infectionJournal of virology · 2025Article
- A single mutation in an enteric virus alters tropism and sensitivity to microbiota.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Norovirus co-opts NINJ1 for selective protein secretion.Science advances · 2025Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 1 country.
Katrina R GrauDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Shu ZhuDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Stefan T PetersonDepartment of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA.
Emily W HelmDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Drake PhilipDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Matthew PhillipsDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Abel HernandezDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Holly TurulaDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.
Philip FrasseDepartment of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-5529-3280
Vincent R GrazianoDepartments of Laboratory Medicine and Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Craig B WilenDepartments of Laboratory Medicine and Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-2495-9403
Christiane E WobusDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.
Megan T BaldridgeDepartment of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA. mbaldridge@wustl.edu.ORCID http://orcid.org/0000-0002-7030-6131
Stephanie M KarstDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA. skarst@ufl.edu.ORCID http://orcid.org/0000-0003-0406-4637
University of Florida · USWashington University in St. Louis · USUniversity of Michigan · USYale University · US
Funding
Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8MComprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2MTraining in Basic and Translational Digestive SciencesT32DK094775 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHN Y KAO, LINDA C. SAMUELSON · 2012 to 2026
$3.6MSuppression of Enteric Norovirus Infection by Microbiota-Regulated Bile AcidsR01AI141478 · NIAID · UNIVERSITY OF FLORIDA · PI KARST, STEPHANIE M · 2019 to 2023
$2.7MIdentification of Host and Viral Determinants of Human Norovirus B cell InfectionR01AI123144 · NIAID · UNIVERSITY OF FLORIDA · PI KARST, STEPHANIE M · 2017 to 2021
$2.3MRole of Intestinal Bacteria in Human Norovirus InfectionR01AI116892 · NIAID · UNIVERSITY OF FLORIDA · PI KARST, STEPHANIE M · 2015 to 2019
$1.8MLack of protective immunity to murine norovirus infectionR01AI081921 · NIAID · UNIVERSITY OF FLORIDA · PI KARST, STEPHANIE M · 2010 to 2013
$1.2MSubversion of gastrointestinal host defenses by norovirusR21AI103961 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WOBUS, CHRISTIANE · 2013 to 2014
$428kRegulation of Interferon-Lambda Signaling by Commensal Bacteria and NorovirusK22AI127846 · NIAID · WASHINGTON UNIVERSITY · PI BALDRIDGE, MEGAN T · 2017 to 2018
$270kNIAID NIH HHS K22 AI127846NIAID NIH HHS R01 AI081921NIAID NIH HHS R01 AI116892NIAID NIH HHS R01 AI123144NIAID NIH HHS R01 AI141478NIAID NIH HHS R21 AI103961NIDCR NIH HHS T90 DE021990NIDDK NIH HHS P30 DK052574NIDDK NIH HHS T32 DK094775
Abstract
Evidence has accumulated to demonstrate that the intestinal microbiota enhances mammalian enteric virus infections
Indexed as
Gastrointestinal MicrobiomeAnimalsBile Acids and SaltsCaliciviridae InfectionsCell LineHost-Pathogen InteractionsHumansInterferon LambdaInterferonsIntestinesMiceMice, Inbred C57BLMice, KnockoutNorovirusOrgan SpecificityBile Acids and SaltsInterferon LambdaInterferons
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.