ArticleNature ecology & evolution2019
Sex-dependent dominance maintains migration supergene in rainbow trout.
Article in Nature ecology & evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 149 papers.
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Who cites it
149 citing papers in PubMed.
- Genetic Structure and Signs of Local Adaptation in Icelandic Brown Trout Populations.Ecology and evolution · 2026Article
- MixedUpParents: A New and Improved Method for Genetic Parentage Assignment in Admixed Populations.Molecular ecology resources · 2026Article
- Divergent habitat selection across many loci maintains species boundaries during introgression.bioRxiv : the preprint server for biology · 2026Article
- Kokanee-sockeye salmon hybridization predominantly leads to a resident life history with outcomes for a long-term reintroduction program.The Journal of heredity · 2026Article
- Characterizing the Distribution ofEvolutionary applications · 2026Article
- Genetic Analysis Reveals Climate Exposure and Conservation Opportunities for a Vulnerable Life History in Steelhead (Evolutionary applications · 2026Article
- Temporal Comparison Reveals Weakened Genotype-Phenotype Association at a Major-Effect Locus in Dworshak National Fish Hatchery Steelhead.Evolutionary applications · 2026Article
- De Novo Genome Assemblies of Four Rainbow Trout Genetic Lines Reveal Structural Variants in Pursuit of a Pangenome Reference.Molecular ecology resources · 2026Article
- Molecular Evolution of a Sex-Linked Inversion Polymorphism in Zebra Finches.Genome biology and evolution · 2026Article
- Ancient but dynamic: structural expansion, massive gene duplication, and transposable element colonization in a supergene controlling ant social organization.Molecular biology and evolution · 2026Article
- A chromosome-level genome for gila trout (Oncorhynchus gilae) provides a novel resource for conservation and management.BMC genomics · 2026Article
- Multiple Genetic Origins of Non-Native, Self-Sustaining Rainbow TroutEvolutionary applications · 2026Article
- Conservation Units for Anadromous Arctic Char (Evolutionary applications · 2026Article
- The geometry of dominance shows broad potential for stable polymorphism under antagonistic pleiotropy.bioRxiv : the preprint server for biology · 2026Article
- Mixed evidence for intralocus sexual conflict from male-limited selection in Drosophila melanogaster.The Journal of heredity · 2026Article
- A genome assembly for Lahontan Cutthroat Trout, Oncorhynchus clarkii henshawi.The Journal of heredity · 2026Article
- Shared and Unique Patterns of Genomic Differentiation and Introgression Between Japanese Stickleback Species Across Three Sympatric Sites.Molecular ecology · 2026Article
- Cosmopolitan inversions have a major impact on trait variation and the power of different GWAS approaches to identify associations.PLoS genetics · 2026Article
- A north-south hemispheric migratory divide in the butterfly Vanessa cardui.Nature communications · 2025Article
- The Genomics Revolution in Nonmodel Species: Predictions vs. Reality for Salmonids.Molecular ecology · 2025Review
89 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
32 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Males and females often differ in their fitness optima for shared traits that have a shared genetic basis, leading to sexual conflict. Morphologically differentiated sex chromosomes can resolve this conflict and protect sexually antagonistic variation, but they accumulate deleterious mutations. However, how sexual conflict is resolved in species that lack differentiated sex chromosomes is largely unknown. Here we present a chromosome-anchored genome assembly for rainbow trout (Oncorhynchus mykiss) and characterize a 55-Mb double-inversion supergene that mediates sex-specific migratory tendency through sex-dependent dominance reversal, an alternative mechanism for resolving sexual conflict. The double inversion contains key photosensory, circadian rhythm, adiposity and sex-related genes and displays a latitudinal frequency cline, indicating environmentally dependent selection. Our results show sex-dependent dominance reversal across a large autosomal supergene, a mechanism for sexual conflict resolution capable of protecting sexually antagonistic variation while avoiding the homozygous lethality and deleterious mutations associated with typical heteromorphic sex chromosomes.
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