ArticleThe ISME journal2020
Wolbachia supplement biotin and riboflavin to enhance reproduction in planthoppers.
Article in The ISME journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
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91 citing papers in PubMed, 165 citations in OpenAlex.
- Wolbachia strain wLhui induces temperature-dependent incomplete cytoplasmic incompatibility in the invasive pest Liriomyza huidobrensis with biocontrol potential.Pest management science · 2026Article
- In Saccharomyces cerevisiae ΔRIB1 and ΔRIB4 mutants, riboflavin auxotrophy is reverted by Wolbachia (wStr) infection.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Silencing LsAtg8 reduces female fecundity and elevates Wolbachia density in embryos of the rice planthopper Laodelphax striatellus.Pest management science · 2026Article
- Alterations in the Gut Microbiome ofInsects · 2026Article
- Genetic Links to Gut Microbiome Variation in the Yellow-Rumped Warbler Hybrid Zone.Molecular ecology · 2026Article
- Evolutionary Genomics of Human Gut Bacteria: Ecological Plasticity Across the Mutualism-Pathogenicity Spectrum.International journal of molecular sciences · 2026Review
- The Bacillus rugosus BPH-S36 genome, a symbiont enabling brown planthopper (Nilaparvata lugens) adaptation to resistant rice.Scientific data · 2026Article
- Three decades of analyzing Wolbachia bacterial endosymbionts in arthropods: Trends and gaps.Parasitology research · 2026Review
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- Defensive symbionts of the European beewolf face competition from brood cell microbiota during vertical transmission.FEMS microbiology ecology · 2026Article
- Genome assembly and protein structure modeling reveal key molecular features of divergentMicrobiology spectrum · 2026Article
- Diversity ofInternational journal of molecular sciences · 2026Article
- Wolbachia-centered cytoplasmic axis links elevational mitochondrial DNA turnover with microbiome restructuring.The ISME journal · 2026Article
- Pathogen promotes insect ovarian development by inducing a dual role of host ATPSyn-β.Communications biology · 2026Article
- Wolbachia enhances ovarian development in the rice planthopper Laodelphax striatellus through elevated energy production.Nature communications · 2025Article
- Article
- Differential gene expression in Chorthippus parallelus (Zetterstedt, 1821) (Orthoptera: Acrididae: Gomphocerinae) induced by Wolbachia infection.Insect science · 2025Article
- Wolbachia-mediated reproductive manipulation in rice planthoppers.Crop health · 2025Review
- Article
- The intracellular symbiont Wolbachia alters Drosophila development and metabolism to buffer against nutritional stress.PLoS genetics · 2025Article
31 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Symbiont-mediated nutritional mutualisms can contribute to the host fitness of insects, especially for those that feed exclusively on nutritionally unbalanced diets. Here, we elucidate the importance of B group vitamins in the association of endosymbiotic bacteria Wolbachia with two plant-sap feeding insects, the small brown planthopper, Laodelphax striatellus (Fallén), and the brown planthopper, Nilaparvata lugens (Stål). Infected planthoppers of both species laid more eggs than uninfected planthoppers, while the experimental transfer of Wolbachia into uninfected lines of one planthopper species rescued this fecundity deficit. The genomic analysis showed that Wolbachia strains from the two planthopper species encoded complete biosynthesis operons for biotin and riboflavin, while a metabolic analysis revealed that Wolbachia-infected planthoppers of both species had higher titers of biotin and riboflavin. Furthermore, experimental supplementation of food with a mixture of biotin and riboflavin recovered the fecundity deficit of Wolbachia-uninfected planthoppers. In addition, comparative genomic analysis suggested that the riboflavin synthesis genes are conserved among Wolbachia supergroups. Biotin operons are rare in Wolbachia, and those described share a recent ancestor that may have been horizontally transferred from Cardinium bacteria. Our research demonstrates a type of mutualism that involves a facultative interaction between Wolbachia and plant-sap feeding insects involving vitamin Bs.
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