ArticleNature communications2019
Interference between overlapping memories is predicted by neural states during learning.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Generalisation between motor and declarative memory sequences: A conceptual replication of Mosha & Robertson (2016).iScience · 2026Article
- The hippocampus rapidly integrates sequence representations during novel multistep predictions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Article
- Test delay and change awareness moderate retroactive and proactive memory effects.Memory & cognition · 2026Article
- Differential representations of spatial environments in mPFC and hippocampus underpinning flexible navigation.NeuroImage · 2026Article
- A role for context-cued study-phase retrievals in episodic memory updating.Memory & cognition · 2026Article
- Related memories exhibit interference during learning in adults but later retrieval in children.PloS one · 2026Article
- Hippocampal-prefrontal orchestration supports higher-order learning for creative ideation.Nature communications · 2025Article
- Beyond Retrieval Competition: Asymmetric Effects of Retroactive and Proactive Interference in Associative Memory.Behavioral sciences (Basel, Switzerland) · 2025Article
- The Hippocampus Rapidly Integrates Sequence Representations During Novel Multistep Predictions.bioRxiv : the preprint server for biology · 2025Article
- Not the same as it ever was: A review of memory modification, updating, and distortion in humans and rodents.Neuroscience and biobehavioral reviews · 2025Review
- Memory updating and the structure of event representations.Trends in cognitive sciences · 2025Review
- The effects of episodic context on memory integration.Scientific reports · 2024Article
- Time after Time: Preserving Temporal Memories When Experiences Repeat.Journal of cognitive neuroscience · 2024Review
- Revisiting the role of computational neuroimaging in the era of integrative neuroscience.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Event Integration and Temporal Differentiation: How Hierarchical Knowledge Emerges in Hippocampal Subfields through Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Receive, Retain and Retrieve: Psychological and Neurobiological Perspectives on Memory Retrieval.Integrative psychological & behavioral science · 2024Article
- Successful generalization of conceptual knowledge after training to remember specific events.Frontiers in cognition · 2024Article
- Neural similarity between overlapping events at learning differentially affects reinstatement across the cortex.NeuroImage · 2023Article
- Interpolated retrieval retroactively increases recall and promotes cross-episode memory interdependence.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- Re-expression of CA1 and entorhinal activity patterns preserves temporal context memory at long timescales.Nature communications · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
One of the primary contributors to forgetting is interference from overlapping memories. Intuitively, this suggests-and prominent theoretical models argue-that memory interference is best avoided by encoding overlapping memories as if they were unrelated. It is therefore surprising that reactivation of older memories during new encoding has been associated with reduced memory interference. Critically, however, prior studies have not directly established why reactivation reduces interference. Here, we first developed a behavioral paradigm that isolates the negative influence that overlapping memories exert during memory retrieval. We then show that reactivating older memories during the encoding of new memories dramatically reduces this interference cost at retrieval. Finally, leveraging multiple fMRI decoding approaches, we show that spontaneous reactivation of older memories during new encoding leads to integration of overlapping memories and, critically, that integration during encoding specifically reduces interference between overlapping, and otherwise competing, memories during retrieval.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.