ArticleNature communications2019
Chemotactic behaviour of Escherichia coli at high cell density.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Bacteria regulate collective behaviour by mechanosensing cell-cell collisions.Nature microbiology · 2026Article
- Cellular scale search and funneling drive bacterial penetration of extreme confinements.Communications physics · 2026Article
- The chemotaxis disruption of Aeromonas veronii by Lactococcus lactis and its probiotic effect on loach (Misgurnus anguillicaudatus).Archives of microbiology · 2026Article
- Emergent Nonlinearity in Active Molecular Chemotaxis.ACS nano · 2026Article
- Collective bacterial condensation is fundamentally constrained by the emergence of active turbulence.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Mixing of a binary passive particle system using smart active particles.Scientific reports · 2025Article
- Control of flagellar gene expression by a chemotaxis receptor-like regulator in pathogenic Escherichia coli.The EMBO journal · 2025Article
- Navigating bacterial motility through chemotaxis: from molecular mechanisms to physiological perspectives.Folia microbiologica · 2025Review
- Experimental evolution partially restores functionality of bacterial chemotaxis network with reduced number of components.PLoS genetics · 2025Article
- Pairwise encounters boost bacterial motion by transient velocity spikes.Biophysical journal · 2025Article
- Motile and Chemotactic Minicells and Minicell-Driven Biohybrids Engineered for Active Cargo Delivery.ACS applied materials & interfaces · 2025Article
- Chemotactic Zn micromotor for treatment of high blood ammonia-associated hepatic encephalopathy.Nature communications · 2025Article
- Role of a single MCP in evolutionary adaptation ofApplied and environmental microbiology · 2025Article
- Self-organization of active plume lattice in bacterial bioconvection.Quantitative biology (Beijing, China) · 2025Article
- Dynamically induced spatial segregation in multispecies bacterial bioconvection.Nature communications · 2025Article
- Swarming bacteria exhibit developmental phase transitions to establish scattered colonies in new regions.The ISME journal · 2025Article
- Surface conversion of the dynamics of bacteria escaping chemorepellents.The European physical journal. E, Soft matter · 2024Article
- Microbes in porous environments: from active interactions to emergent feedback.Biophysical reviews · 2024Review
- Direct measurement of dynamic attractant gradients reveals breakdown of the Patlak-Keller-Segel chemotaxis model.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- D-amino acids signal a stress-dependent run-away response in Vibrio cholerae.Nature microbiology · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
At high cell density, swimming bacteria exhibit collective motility patterns, self-organized through physical interactions of a however still debated nature. Although high-density behaviours are frequent in natural situations, it remained unknown how collective motion affects chemotaxis, the main physiological function of motility, which enables bacteria to follow environmental gradients in their habitats. Here, we systematically investigate this question in the model organism Escherichia coli, varying cell density, cell length, and suspension confinement. The characteristics of the collective motion indicate that hydrodynamic interactions between swimmers made the primary contribution to its emergence. We observe that the chemotactic drift is moderately enhanced at intermediate cell densities, peaks, and is then strongly suppressed at higher densities. Numerical simulations reveal that this suppression occurs because the collective motion disturbs the choreography necessary for chemotactic sensing. We suggest that this physical hindrance imposes a fundamental constraint on high-density behaviours of motile bacteria, including swarming and the formation of multicellular aggregates and biofilms.
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