ArticleJournal of genetics2019
X-chromosome genetic association test incorporating X-chromosome inactivation and imprinting effects.
Article in Journal of genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation.BMC bioinformatics · 2022Article
- Gene-Based Methods for Estimating the Degree of the Skewness of X Chromosome Inactivation.Genes · 2022Article
- A statistical measure for the skewness of X chromosome inactivation for quantitative traits and its application to the MCTFR data.BMC genomic data · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies have shown that many complex diseases are sex-determined. When conducting genetic association studies on X-chromosome, there are two important epigenetic factors which should be considered simultaneously: X-chromosome inactivation and genomic imprinting. Currently, there have been several association tests accounting for the information on X-chromosome inactivation. However, these tests do not take the imprinting effects into account. In this paper, we propose a novel association test simultaneously incorporating X-chromosome inactivation and imprinting effects based on case-parent trios and control-parent trios for female offspring and case-control data for male offspring, denoted by
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