Evidence map›Paper›PMID 31767773›Full record

ArticleInfection and immunity2020

Aspergillus fumigatus Cell Wall Promotes Apical Airway Epithelial Recruitment of Human Neutrophils.

Michael B Feldman, Richard A Dutko, Michael A Wood, Rebecca A Ward, Hui Min Leung, Ryan F Snow, Denis J De La Flor, Lael M Yonker, Jennifer L Reedy, Guillermo J Tearney and 3 more

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Early immune response toMicrobiology spectrum · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Epithelial responses to fungal pathogens.Current opinion in microbiology · 2024
    Review
  11. Article
  12. Article
  13. International journal of molecular sciences · 2023
    Article
  14. Review
  15. Article
  16. Immunity to fungi in the lung.Seminars in immunology · 2023
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Michael B FeldmanDivision of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Richard A DutkoDivision of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, USA.
Michael A WoodDepartment of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Rebecca A WardDivision of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, USA.
Hui Min LeungWellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Ryan F SnowDepartment of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Denis J De La FlorDepartment of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Lael M YonkerDepartment of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jennifer L ReedyDivision of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, USA.
Guillermo J TearneyWellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Hongmei MouDepartment of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Bryan P HurleyDepartment of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jatin M VyasDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA jvyas@mgh.harvard.edu.ORCID 0000-0002-9985-9565
Massachusetts General Hospital · USHarvard University · USBoston Children's Hospital · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Research Training in Pulmonary Immunology and Allergy at MGHT32HL116275 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI David C Christiani, ANDREW D LUSTER · 2013 to 2026
$8.6M
Harvard Clinical and Translational Science CenterKL2TR001100 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$8.5M
The Role of Hepoxilin A3 in Neutrophil Breach of the Infected Airway MucosaR01AI095338 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HURLEY, BRYAN P · 2012 to 2022
$5.2M
The Functional Role of the Tetraspanin CD82/Kai1 in Fungal Innate ImmunityR01AI136529 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI VYAS, JATIN M · 2018 to 2022
$2.7M
Functional Role of the Tetraspanin CD82/Kai1 in Innate and Adaptive ImmunityR01AI092084 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI VYAS, JATIN M · 2011 to 2015
$2.2M
Innate Immune Response to Aspergillus fumigatus Cell Wall CarbohydratesK08AI141755 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI REEDY, JENNIFER LYNNE · 2019 to 2022
$799k
NCATS NIH HHS KL2 TR001100NHLBI NIH HHS T32 HL116275NIAID NIH HHS K08 AI141755NIAID NIH HHS R01 AI095338NIAID NIH HHS R01 AI136529
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AspergillosisAspergillus fumigatusCell Line, TumorCell WallEpithelial CellsHumansLungMelaninsNaphtholsNeutrophilsSpores, Fungal1,8-dihydroxynaphthalene melaninMelaninsNaphtholsAspergillus fumigatusepithelial cellshost-pathogen interactionsneutrophilsrespiratory pathogens

Identifiers

PMID31767773
PMCPMC6977131
OpenAlexW2989770844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.