Evidence map›Paper›PMID 31767637›Full record

ArticleG3 (Bethesda, Md.)2020

A Genetic Screen for Genes That Impact Peroxisomes in

Hillary K Graves, Sharayu Jangam, Kai Li Tan, Antonella Pignata, Elaine S Seto, Shinya Yamamoto, Michael F Wangler

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. International journal of molecular sciences · 2025
    Article
  2. Article
  3. The role of Evi/Wntless in exporting Wnt proteins.Development (Cambridge, England) · 2023
    Review
  4. Article
  5. Investigating Developmental and Epileptic Encephalopathy UsingInternational journal of molecular sciences · 2020
    Review
  6. Rosy Beginnings: Studying Peroxisomes inFrontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hillary K GravesDepartment of Molecular and Human Genetics.
Sharayu JangamDepartment of Molecular and Human Genetics.ORCID 0000-0001-7389-0890
Kai Li TanDepartment of Molecular and Human Genetics.ORCID 0000-0002-1450-7916
Antonella PignataDepartment of Molecular and Human Genetics.
Elaine S SetoDepartment of Molecular and Human Genetics.
Shinya YamamotoDepartment of Molecular and Human Genetics, yamamoto@bcm.edu mw147467@bcm.edu.ORCID 0000-0003-2172-8036
Michael F WanglerDepartment of Molecular and Human Genetics, yamamoto@bcm.edu mw147467@bcm.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxisomes are subcellular organelles that are essential for proper function of eukaryotic cells. In addition to being the sites of a variety of oxidative reactions, they are crucial regulators of lipid metabolism. Peroxisome loss or dysfunction leads to multi-system diseases in humans that strongly affect the nervous system. In order to identify previously unidentified genes and mechanisms that impact peroxisomes, we conducted a genetic screen on a collection of lethal mutations on the

Indexed as

Genes, InsectSequence Homology, Nucleic AcidAnimalsDrosophila melanogasterHumansMutationPeroxisomesX ChromosomeZellweger SyndromeBRD4Drosophilafs(1)hperoxisomes

Identifiers

PMID31767637
PMCPMC6945042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.