Evidence map›Paper›PMID 31767584›Full record

Trial reportBMJ open2019

Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms.

Thomas Ott, Jascha Stracke, Susanna Sellin, Marc Kriege, Gerrit Toenges, Carsten Lott, Sebastian Kuhn, Kristin Engelhard

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Thomas OttDepartment of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany ottth@uni-mainz.de.ORCID 0000-0001-7510-7679
Jascha StrackeDepartment of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
Susanna SellinDepartment of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
Marc KriegeDepartment of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
Gerrit ToengesInstitute of Medical Biostatistics, Epidemiology and Informatics, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
Carsten LottDepartment of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
Sebastian KuhnDepartment of Orthopaedics and Traumatology, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
Kristin EngelhardDepartment of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDuring a 'cannot intubate, cannot oxygenate' situation, asphyxia can lead to cardiac arrest. In this stressful situation, two complex algorithms facilitate decision-making to save a patient's life: difficult airway management and cardiopulmonary resuscitation. However, the extent to which competition between the two algorithms causes conflicts in the execution of pivotal treatment remains unknown. Due to the rare incidence of this situation and the very low feasibility of such an evaluation in clinical reality, we decided to perform a randomised crossover simulation research study. We propose that even experienced healthcare providers delay cricothyrotomy, a lifesaving approach, due to concurrent cardiopulmonary resuscitation in a 'cannot intubate, cannot oxygenate' situation.

designDue to the rare incidence and dynamics of such a situation, we conducted a randomised crossover simulation research study.

settingWe collected data in our institutional simulation centre between November 2016 and November 2017.

participantsWe included 40 experienced staff anaesthesiologists at our tertiary university hospital centre.

interventionThe participants treated two simulated patients, both requiring cricothyrotomy: one patient required cardiopulmonary resuscitation due to asphyxia, and one patient did not require cardiopulmonary resuscitation. Cardiopulmonary resuscitation was the intervention. Participants were evaluated by video records. PRIMARY OUTCOME MEASURES: The difference in 'time to ventilation through cricothyrotomy' between the two situations was the primary outcome measure.

resultsThe results of 40 participants were analysed. No carry-over effects were detected in the crossover design. During cardiopulmonary resuscitation, the median time to ventilation was 22 s (IQR 3-40.5) longer than that without cardiopulmonary resuscitation (p=0.028), including the decision-making time.

conclusionCricothyrotomy, which is the most crucial treatment for cardiac arrest in a 'cannot intubate, cannot oxygenate' situation, was delayed by concurrent cardiopulmonary resuscitation. If cardiopulmonary resuscitation delays cricothyrotomy, it should be interrupted to first focus on cricothyrotomy.

Indexed as

Airway ManagementAlgorithmsCardiopulmonary ResuscitationClinical Decision-MakingAdultCross-Over StudiesFemaleHeart ArrestHigh Fidelity Simulation TrainingHumansLaryngeal MusclesMalePatient SelectionAirway Management [E02.041]Anesthesiology [H02.403.066]Cardiopulmonary Resuscitation [E02.365.647.110]Manikins [J01.897.280.500.545.129.400][MeSH Tree numbers]: Simulation

Identifiers

PMID31767584
PMCPMC6887030
OpenAlexW2990139361

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.