Evidence map›Paper›PMID 31767054›Full record

ArticleeLife2019

Design of biochemical pattern forming systems from minimal motifs.

Philipp Glock, Fridtjof Brauns, Jacob Halatek, Erwin Frey, Petra Schwille

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Bridging scales in a multiscale pattern-forming system.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Turing Patterning in Stratified Domains.Bulletin of mathematical biology · 2020
    Article
  14. C-terminal eYFP fusion impairsOpen biology · 2020
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philipp Glock *Max-Planck-Institute of Biochemistry, Martinsried, Germany.ORCID 0000-0002-0238-2634
Fridtjof Brauns *Arnold Sommerfeld Center for Theoretical Physics, Department of Physics, Ludwig-Maximilians-Universität München, München, Germany.ORCID 0000-0002-6108-9278
Jacob Halatek *Arnold Sommerfeld Center for Theoretical Physics, Department of Physics, Ludwig-Maximilians-Universität München, München, Germany.ORCID 0000-0003-3211-2253
Erwin FreyArnold Sommerfeld Center for Theoretical Physics, Department of Physics, Ludwig-Maximilians-Universität München, München, Germany.ORCID 0000-0001-8792-3358
Petra SchwilleMax-Planck-Institute of Biochemistry, Martinsried, Germany.ORCID 0000-0002-6106-4847

Funding

Deutsche Forschungsgemeinschaft GRK2062Deutsche Forschungsgemeinschaft SFB1032 (Project-ID 201269156)Max-Planck-Gesellschaft International Max Planck Research School for Molecular and Cellular Life Sciences
6 · The paper itself

Abstract

Although molecular self-organization and pattern formation are key features of life, only very few pattern-forming biochemical systems have been identified that can be reconstituted and studied in vitro under defined conditions. A systematic understanding of the underlying mechanisms is often hampered by multiple interactions, conformational flexibility and other complex features of the pattern forming proteins. Because of its compositional simplicity of only two proteins and a membrane, the MinDE system from

Indexed as

AlgorithmsModels, TheoreticalNucleotide MotifsProtein ConformationProtein MultimerizationAdenosine TriphosphatasesBase SequenceCell Cycle ProteinsCell DivisionCell MembraneEscherichia coliEscherichia coli ProteinsAdenosine TriphosphatasesCell Cycle ProteinsEscherichia coli ProteinsMinD protein, E coliMinE protein, E coliE. coliin vitro reconstitutionmin systempattern formationphysics of living systemsreaction-diffusionself-organization

Identifiers

PMID31767054
PMCPMC6922632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.