ArticleBMC medicine2019
Challenges in management and prevention of ischemic heart disease in low socioeconomic status people in LLMICs.
Article in BMC medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Prevalence of ischemic heart disease among cardiac patients in Ethiopia: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Development and assessment of scoring model for ICU stay and mortality prediction after emergency admissions in ischemic heart disease: a retrospective study of MIMIC-IV databases.Internal and emergency medicine · 2023Trial
- Risk prediction and prevention in patients with advanced subclinical atherosclerosis.BMC cardiovascular disorders · 2026Review
- Ischemic heart disease burden and healthcare system readiness across sub-Saharan Africa.Nature cardiovascular research · 2026Review
- The national and subnational trend of ischemic heart disease in Iran from 1990-2021, with projections for 2040: a modelling study.American journal of cardiovascular disease · 2026Article
- Cardiovascular hospitalization dynamics in Iran's second-largest city: A spatial and temporal perspective.PloS one · 2026Article
- Global, regional, and national burden of ischaemic heart disease from 1990 to 2021: a comprehensive analysis based on the Global Burden of Disease study 2021.Journal of global health · 2025Article
- Global, regional, and national burden of ischemic heart disease in young and middle-aged population from 1990 to 2021.Scientific reports · 2025Article
- Spatial-temporal characteristics and prediction of ischemic heart disease burden in the working population aged 15 to 59 years in China.Frontiers in cardiovascular medicine · 2025Article
- Global, regional, and national burdens of ischemic heart disease in the older adults aged 60-89 years: a systematic analysis for the Global Burden of Disease Study 2019.Frontiers in cardiovascular medicine · 2025Article
- Preventing premature cardiovascular mortality: the role of lifestyle interventions and pharmacotherapy-a narrative review.Frontiers in cardiovascular medicine · 2025Review
- Adverse events of tissue plasminogen activators in acute myocardial infarction patients: a real-world and pharmacovigilance database analysis.BMC cardiovascular disorders · 2024Article
- The global burden of ischemic heart disease attributed to high fasting plasma glucose: Data from 1990 to 2019.Heliyon · 2024Article
- Burden of cardiovascular disease among elderly: based on the Global Burden of Disease Study 2019.European heart journal. Quality of care & clinical outcomes · 2024Article
- Presentation, care, and outcomes of patients with NSTEMI according to World Bank country income classification: the ACVC-EAPCI EORP NSTEMI Registry of the European Society of Cardiology.European heart journal. Quality of care & clinical outcomes · 2023Article
- Global, regional and national estimates of influenza-attributable ischemic heart disease mortality.EClinicalMedicine · 2023Article
- Implementing a multisector public-private partnership to improve urban hypertension management in low-and middle- income countries.BMC public health · 2022Article
- Association of health insurance status with coronary risk factors, coronary artery disease, interventions and outcomes in India.International journal of cardiology. Cardiovascular risk and prevention · 2022Article
- Perceived cardiovascular disease risk and tailored communication strategies among rural and urban community dwellers in Rwanda: a qualitative study.BMC public health · 2022Article
- Global, regional, and national burden of ischaemic heart disease and its attributable risk factors, 1990-2017: results from the Global Burden of Disease Study 2017.European heart journal. Quality of care & clinical outcomes · 2022Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular diseases, principally ischemic heart disease (IHD), are the most important cause of death and disability in the majority of low- and lower-middle-income countries (LLMICs). In these countries, IHD mortality rates are significantly greater in individuals of a low socioeconomic status (SES). MAIN TEXT: Three important focus areas for decreasing IHD mortality among those of low SES in LLMICs are (1) acute coronary care; (2) cardiac rehabilitation and secondary prevention; and (3) primary prevention. Greater mortality in low SES patients with acute coronary syndrome is due to lack of awareness of symptoms in patients and primary care physicians, delay in reaching healthcare facilities, non-availability of thrombolysis and coronary revascularization, and the non-affordability of expensive medicines (statins, dual anti-platelets, renin-angiotensin system blockers). Facilities for rapid diagnosis and accessible and affordable long-term care at secondary and tertiary care hospitals for IHD care are needed. A strong focus on the social determinants of health (low education, poverty, working and living conditions), greater healthcare financing, and efficient primary care is required. The quality of primary prevention needs to be improved with initiatives to eliminate tobacco and trans-fats and to reduce the consumption of alcohol, refined carbohydrates, and salt along with the promotion of healthy foods and physical activity. Efficient primary care with a focus on management of blood pressure, lipids and diabetes is needed. Task sharing with community health workers, electronic decision support systems, and use of fixed-dose combinations of blood pressure-lowering drugs and statins can substantially reduce risk factors and potentially lead to large reductions in IHD. Finally, training of physicians, nurses, and health workers in IHD prevention should be strengthened.
conclusionThe management and prevention of IHD in individuals with a low SES in LLMICs are poor. Greater availability, access, and affordability for acute coronary syndrome management and secondary prevention are important. Primary prevention should focus on tackling the social determinants of health as well as policy and individual interventions for risk factor control, supported by task sharing and use of technology.
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