Evidence map›Paper›PMID 31766654›Full record

ArticleMolecules (Basel, Switzerland)2019

Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats.

Magdalena Górny, Agnieszka Wnuk, Adrianna Kamińska, Kinga Kamińska, Grażyna Chwatko, Anna Bilska-Wilkosz, Małgorzata Iciek, Małgorzata Kajta, Zofia Rogóż, Elżbieta Lorenc-Koci

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Magdalena GórnyThe Chair of Medical Biochemistry, Jagiellonian University Medical College, 7 Kopernika Street, 31-034 Kraków, Poland.ORCID 0000-0002-6393-9977
Agnieszka WnukMaj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.ORCID 0000-0003-3620-3902
Adrianna KamińskaDepartment of Environmental Chemistry, University of Łódź, 163 Pomorska Street, 90-236 Łódź, Poland.
Kinga KamińskaMaj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.
Grażyna ChwatkoDepartment of Environmental Chemistry, University of Łódź, 163 Pomorska Street, 90-236 Łódź, Poland.ORCID 0000-0001-9247-5131
Anna Bilska-WilkoszThe Chair of Medical Biochemistry, Jagiellonian University Medical College, 7 Kopernika Street, 31-034 Kraków, Poland.ORCID 0000-0001-9066-6292
Małgorzata IciekThe Chair of Medical Biochemistry, Jagiellonian University Medical College, 7 Kopernika Street, 31-034 Kraków, Poland.ORCID 0000-0002-0422-0428
Małgorzata KajtaMaj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.
Zofia RogóżMaj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.
Elżbieta Lorenc-KociMaj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.ORCID 0000-0002-9970-8548
Maj Institute of Pharmacology · PLJagiellonian University · PLUniversity of Łódź · PL

Funding

National Science Centre of Poland UMO-2016/23/B/NZ7/01280
6 · The paper itself

Abstract

Impaired glutathione (GSH) synthesis and dopaminergic transmission are important factors in the pathophysiology of schizophrenia. Our research aimed to assess the effects of l-buthionine-(

Indexed as

Amino Acids, SulfurAnimalsButhionine SulfoximineDisease Models, AnimalDNA MethylationGlutathioneHomeostasisMalePiperazinesRatsRats, Sprague-DawleySchizophreniaAmino Acids, SulfurButhionine SulfoximineGlutathionePiperazinesvanoxerineglobal DNA methylationGSH deficiencyneurodevelopmental model of schizophreniasocial and cognitive deficitssulfur amino acids levels

Identifiers

PMID31766654
PMCPMC6930621
OpenAlexW2989595507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.