Evidence map›Paper›PMID 31766544›Full record

ReviewMolecules (Basel, Switzerland)2019

Phytofabrication of Nanoparticles as Novel Drugs for Anticancer Applications.

Qi-Yao Wei, Kai-Ming He, Jin-Ling Chen, Yan-Ming Xu, Andy T Y Lau

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Phyto-synthesized silver nanoparticles fromFrontiers in plant science · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Recent Advances in Phenolic Metabolites and Skin Cancer.International journal of molecular sciences · 2021
    Review
  15. Review
  16. Review
  17. Review
  18. Mitochondrial nanotargeting in malignancies (Review).Experimental and therapeutic medicine · 2020
    Review
  19. Natural Metallic Nanoparticles for Application in Nano-Oncology.International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qi-Yao WeiLaboratory of Cancer Biology and Epigenetics, Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, Guangdong 515041, China.ORCID 0000-0002-8334-8912
Kai-Ming HeLaboratory of Cancer Biology and Epigenetics, Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, Guangdong 515041, China.ORCID 0000-0002-7735-569X
Jin-Ling ChenLaboratory of Cancer Biology and Epigenetics, Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, Guangdong 515041, China.ORCID 0000-0002-8941-567X
Yan-Ming XuLaboratory of Cancer Biology and Epigenetics, Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, Guangdong 515041, China.ORCID 0000-0003-1124-0045
Andy T Y LauLaboratory of Cancer Biology and Epigenetics, Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, Guangdong 515041, China.ORCID 0000-0002-7146-7789
Shantou University · CN

Funding

National Natural Science Foundation of China National Natural Science Foundation of China (Nos. 31771582 31271445Natural Science Foundation of Guangdong Province 2017A030313131
6 · The paper itself

Abstract

Cancer is one of the foremost causes of death globally and also the major stumbling block of increasing life expectancy. Although the primary treatment of surgical resection, chemotherapy, and radiotherapy have greatly reduced the mortality of cancer, the survival rate is still low because of the metastasis of tumor, a range of adverse drug reactions, and drug resistance. For all this, it is relevant to mention that a growing amount of research has shown the anticarcinogenic effect of phytochemicals which can modulate the molecular pathways and cellular events include apoptosis, cell proliferation, migration, and invasion. However, their pharmacological potential is hindered by their low water solubility, low stability, poor absorption, and rapid metabolism. In this scenario, the development of nanotechnology has created novel formulations to maximize the potential use of phytochemicals in anticancer treatment. Nanocarriers can enhance the solubility and stability of phytochemicals, prolong their half-life in blood and even achieve site-targeting delivery. This review summarizes the advances in utilizing nanoparticles in cancer therapy. In particular, we introduce several applications of nanoparticles combined with apigenin, resveratrol, curcumin, epigallocatechin-3-gallate, 6-gingerol, and quercetin in cancer treatment.

Indexed as

Drug Delivery SystemsAntineoplastic Agents, PhytogenicHumansNanoparticlesNeoplasmsAntineoplastic Agents, Phytogenicanticancernanoparticlesnanophytochemicalsphytochemicalsphytofabrication

Identifiers

PMID31766544
PMCPMC6930546
OpenAlexW2990969845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.