Evidence map›Paper›PMID 31766400›Full record

ArticleInternational journal of environmental research and public health2019

The Association of Environmental Tobacco Smoke Exposure and Inflammatory Markers in Hospitalized Children.

E Melinda Mahabee-Gittens, Ashley L Merianos, Patricia C Fulkerson, Lara Stone, Georg E Matt

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02531594 (An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02531594 nacompletednot on this map

An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients

TypeinterventionalSponsorChildren's Hospital Medical Center, CincinnatiRan2016 to 2022Enrolled770ConditionsSmoking CessationArmsSBIRT, HHC
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Observational
  2. Article
  3. Social Inequalities: Do They Matter in Asthma, Bronchitis, and Respiratory Symptoms in Children?International journal of environmental research and public health · 2022
    Article
  4. Respiratory Symptoms, Allergies, and Environmental Exposures in Children with and without Asthma.International journal of environmental research and public health · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

E Melinda Mahabee-GittensDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center; University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.ORCID 0000-0002-3893-885X
Ashley L MerianosSchool of Human Services, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0002-5640-7227
Patricia C FulkersonDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati; College of Medicine, Cincinnati, OH 45229, USA.
Lara StoneDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center; University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
Georg E MattDepartment of Psychology, San Diego State University, San Diego, CA 92123, USA.
Cincinnati Children's Hospital Medical Center · USSan Diego State University · USUniversity of Cincinnati · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$9.9M
Prevalence and Clinical Correlates of Thirdhand Smoke Exposure in a Pediatric Patient PopulationR01ES030743 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI MAHABEE-GITTENS, E. MELINDA · 2019 to 2023
$2.9M
Reducing Secondhand Smoke Exposure Among Pediatric Patients in the Emergency Department SettingK01DA044313 · NIDA · UNIVERSITY OF CINCINNATI · PI MERIANOS, ASHLEY L · 2017 to 2021
$727k
NCATS NIH HHS 8UL1TR000077NCATS NIH HHS UL1 TR001425NCI NIH HHS 3R21CA184337S1NIDA NIH HHS K01 DA044313NIDA NIH HHS K01DA044313NIEHS NIH HHS R01ES030743
6 · The paper itself

Abstract

backgroundEnvironmental tobacco smoke (ETS) exposure is associated with altered cytokine levels in children. We sought to examine ETS exposure prevalence and the relationship between ETS exposure and cytokine levels in a sample of hospitalized children. (2) Methods: Inflammatory markers (IL-8, IL-1β, IL-10, and TNF-α) and cotinine were measured in saliva of hospitalized, nonsmoking children (N = 112). To assess the association between ETS exposure and immune system response, we built a multivariate regression model including the four inflammatory markers as the response variables and cotinine, age, sex, and discharge diagnosis as explanatory variables while assessing possible interaction effects. (3) Results: Mean age (SD) was 5.8(5.0) years; Geometric Mean (GeoM) cotinine = 1.8 [95% CI = 1.4-2.2]. Children with non-inflammatory other diagnoses had lower IL-10 (

Indexed as

AdolescentAsthmaBiomarkersChildChild, HospitalizedChild, PreschoolCotinineEnvironmental ExposureFemaleHumansInfantInfant, NewbornInflammationInterleukin-1betaMaleSalivaBiomarkersCotinineIL1B protein, humanInterleukin-1betaTobacco Smoke Pollutionchildrencotininecytokinesinflammatory markerssecondhand smoke exposure

Identifiers

PMID31766400
PMCPMC6926853
OpenAlexW2990590678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.