Evidence map›Paper›PMID 31766389›Full record

ArticleCells2019

Comparison of the Effect of Two Hyaluronic Acid Preparations on Fibroblast and Endothelial Cell Functions Related to Angiogenesis.

Valerio Ciccone, Marco Zazzetta, Lucia Morbidelli

Open access · goldAbstract readComparative Study
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Hyaluronic Acid ProfhiloMedicina (Kaunas, Lithuania) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Histological Comparison of Lipofilling and Hyaluronic Acid Filler Injection 30 Days after Simulation in Rats.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Low molecular weight hyaluronan inhibits lung epithelial ion channels by activating the calcium-sensing receptor.Matrix biology : journal of the International Society for Matrix Biology · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Valerio CicconeDepartment of Life Sciences, University of Siena, 53100 Siena, Italy.
Marco ZazzettaRegenyal Laboratories Srl, 63074 San Benedetto del Tronto (AP), Italy.
Lucia MorbidelliDepartment of Life Sciences, University of Siena, 53100 Siena, Italy.
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyaluronic acid (HA) is used in substitutive and aesthetic medicine with various applications. Ultrapure absorbable HA (Bioregen

Indexed as

Angiogenesis Inducing AgentsAnimalsCell LineCell MovementCell ProliferationCells, CulturedCell SurvivalEndothelial CellsFibroblastsHumansHuman Umbilical Vein Endothelial CellsHyaluronic AcidMaleMiceMice, Inbred C57BLNeovascularization, PhysiologicAngiogenesis Inducing AgentsHyaluronic Acidangiogenesisfibroblastshyaluronic acid

Identifiers

PMID31766389
PMCPMC6952963
OpenAlexW2990441106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.