Evidence map›Paper›PMID 31766274›Full record

ArticleMethods and protocols2019

Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene

Lisa Hölzl-Armstrong, Jill E Kucab, Michael Korenjak, Mirjam Luijten, David H Phillips, Jiri Zavadil, Volker M Arlt

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods and protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Lisa Hölzl-ArmstrongDepartment of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.
Jill E KucabDepartment of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.
Michael KorenjakMolecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, 69008 Lyon, France.
Mirjam LuijtenCenter for Health Protection, National Institute for Public Health and the Environment (RIVM), 3721 MA Bilthoven, The Netherlands.
David H PhillipsDepartment of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.
Jiri ZavadilMolecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, 69008 Lyon, France.
Volker M ArltDepartment of Analytical, Environmental and Forensic Sciences, King's College London, London SE1 9NH, UK.
King's College London · GBCentre international de recherche sur le cancer · FRNational Institute for Public Health and the Environment · NL

Funding

Cancer Research UK C98/A24032World Health Organization 001
6 · The paper itself

Abstract

DNA in dividing cells is prone to mutagenesis, with mutations making key contributions to human disease including cancer. The tumour suppressor gene

Indexed as

cancer aetiologyDNA adductsembryonic fibroblastsenvironmental carcinogenesisgenotoxicityimmortalisationmouse modelmutationNutlin-3atumour suppressor p53

Identifiers

PMID31766274
PMCPMC6961128
OpenAlexW2989287504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.