Evidence map›Paper›PMID 31766249›Full record

ArticleInternational journal of molecular sciences2019

Conditional Deletion of Dicer in Adult Mice Impairs Skeletal Muscle Regeneration.

Satoshi Oikawa, Minjung Lee, Takayuki Akimoto

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. MicroRNAs as the Sentinels of Redox and Hypertrophic Signalling.International journal of molecular sciences · 2022
    Review
  5. Skeletal Muscle Regeneration in Cardiotoxin-Induced Muscle Injury Models.International journal of molecular sciences · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Satoshi OikawaFaculty of Sport Sciences, Waseda University, Saitama 359-1192, Japan.ORCID 0000-0002-7696-8128
Minjung LeeFaculty of Sport Sciences, Waseda University, Saitama 359-1192, Japan.
Takayuki AkimotoFaculty of Sport Sciences, Waseda University, Saitama 359-1192, Japan.
Waseda University · JP

Funding

Japan Society for the Promotion of Science 21680049Japan Society for the Promotion of Science 8680047
6 · The paper itself

Abstract

Skeletal muscle has a remarkable regenerative capacity, which is orchestrated by multiple processes, including the proliferation, fusion, and differentiation of the resident stem cells in muscle. MicroRNAs (miRNAs) are small noncoding RNAs that mediate the translational repression or degradation of mRNA to regulate diverse biological functions. Previous studies have suggested that several miRNAs play important roles in myoblast proliferation and differentiation in vitro. However, their potential roles in skeletal muscle regeneration in vivo have not been fully established. In this study, we generated a mouse in which the

Indexed as

RegenerationAnimalsCells, CulturedDEAD-box RNA HelicasesGene DeletionMiceMice, KnockoutMicroRNAsMuscle DevelopmentMuscle, SkeletalRibonuclease IIIDEAD-box RNA HelicasesDicer1 protein, mouseMicroRNAsRibonuclease IIIDicermicroRNAmuscle regenerationskeletal muscle

Identifiers

PMID31766249
PMCPMC6887938
OpenAlexW2988453505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.