Evidence map›Paper›PMID 31766216›Full record

Trial reportNutrients2019

New Zealand Bitter Hops Extract Reduces Hunger During a 24 h Water Only Fast.

Edward Walker, Kim Lo, Sze Tham, Malcolm Pahl, Dominic Lomiwes, Janine Cooney, Mark Wohlers, Pramod Gopal

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. The Promising Ability ofMolecules (Basel, Switzerland) · 2021
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. An Updated Review of the GenusPlants (Basel, Switzerland) · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Edward WalkerThe New Zealand Institute for Plant and Food Research Limited, Auckland 1025, New Zealand.ORCID 0000-0003-3080-8791
Kim LoThe New Zealand Institute for Plant and Food Research Limited, Auckland 1025, New Zealand.
Sze ThamThe New Zealand Institute for Plant and Food Research Limited, Palmerston North 4442, New Zealand.ORCID 0000-0001-6380-774X
Malcolm PahlThe New Zealand Institute for Plant and Food Research Limited, Auckland 1025, New Zealand.ORCID 0000-0001-8757-3394
Dominic LomiwesThe New Zealand Institute for Plant and Food Research Limited, Palmerston North 4442, New Zealand.
Janine CooneyThe New Zealand Institute for Plant and Food Research Limited, Hamilton 3240, New Zealand.ORCID 0000-0002-2547-0100
Mark WohlersThe New Zealand Institute for Plant and Food Research Limited, Auckland 1025, New Zealand.
Pramod GopalThe New Zealand Institute for Plant and Food Research Limited, Palmerston North 4442, New Zealand.ORCID 0000-0002-3434-5555
Plant & Food Research · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intermittent fasting improves metabolic and cardiac health. However, increased hunger towards the end of the fasting period may affect compliance and limit its application. Our aim was to determine the effect of anorexigenic agent co-therapy on subjective ratings of appetite during the 16-24 h period of a day-long water-only intermittent fast. Thirty adult men were recruited and required to fast for 24 h from 18:00 h to 18:00 h on the same day of the week for three subsequent weeks. Treatments of either a placebo or one of two doses (high dose; HD: 250 mg or low dose; LD: 100 mg) of a bitter hops-based appetite suppressant (Amarasate®) were given twice per day at 16 and 20 h into the fast. From 18-24 h of the 24 h fast, both the HD and LD treatment groups exhibited a statistically significant (

Indexed as

FastingWaterAdultCross-Over StudiesDose-Response Relationship, DrugDouble-Blind MethodHumansHumulusHungerMaleMiddle AgedNew ZealandPlant ExtractsYoung AdultPlant ExtractsWaterAmarasate®appetitebitter brakebitter taste receptorscalorie restrictiondietary supplementIntermittent fastingsatietytime–restricted eatingwater fasting

Identifiers

PMID31766216
PMCPMC6893682
OpenAlexW2983775608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.