Evidence map›Paper›PMID 31766208›Full record

ReviewMicroorganisms2019

Gut Bacteria and their Metabolites: Which One Is the Defendant for Colorectal Cancer?

Samira Tarashi, Seyed Davar Siadat, Sara Ahmadi Badi, Mohammadreza Zali, Roberto Biassoni, Mirco Ponzoni, Arfa Moshiri

Abstract readReview
In one paragraph

Review in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effects of Tumor-associatedArchives of Razi Institute · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Microbiota medicine: towards clinical revolution.Journal of translational medicine · 2022
    Review
  15. CombiningFrontiers in microbiology · 2022
    Article
  16. Article
  17. Article
  18. Spot-light on microbiota in obesity and cancer.International journal of obesity (2005) · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samira TarashiMicrobiology Research Center, Pasteur Institute of Iran, 1316943551 Tehran, Iran.
Seyed Davar SiadatMicrobiology Research Center, Pasteur Institute of Iran, 1316943551 Tehran, Iran.ORCID 0000-0002-6892-5603
Sara Ahmadi BadiMicrobiology Research Center, Pasteur Institute of Iran, 1316943551 Tehran, Iran.
Mohammadreza ZaliGastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, 19857-17411 Tehran, Iran.
Roberto BiassoniLaboratory of Molecular Medicine, IRCCS Instituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-4365-8166
Mirco PonzoniLaboratory of Experimental Therapies in Oncology, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-6164-4286
Arfa MoshiriGastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, 19857-17411 Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a worldwide health concern which requires efficient therapeutic strategies. The mechanisms underlying CRC remain an essential subject of investigations in the cancer biology field. The evaluation of human microbiota can be critical in this regard, since the disruption of the normal community of gut bacteria is an important issue in the development of CRC. However, several studies have already evaluated the different aspects of the association between microbiota and CRC. The current study aimed at reviewing and summarizing most of the studies on the modifications of gut bacteria detected in stool and tissue samples of CRC cases. In addition, the importance of metabolites derived from gut bacteria, their relationship with the microbiota, and epigenetic modifications have been evaluated.

Indexed as

colorectal cancerdysbiosisepigeneticsgut bacteria

Identifiers

PMID31766208
PMCPMC6920974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.