Evidence map›Paper›PMID 31766145›Full record

ArticlePharmaceutics2019

Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules.

Mary-Carmel Kearney, Peter E McKenna, Helen L Quinn, Aaron J Courtenay, Eneko Larrañeta, Ryan F Donnelly

Abstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Progressive microneedles for targeting and intelligent drug delivery.Asian journal of pharmaceutical sciences · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mary-Carmel KearneySchool of Pharmacy, Queen's University, Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Peter E McKennaSchool of Pharmacy, Queen's University, Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Helen L QuinnSchool of Pharmacy, Queen's University, Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Aaron J CourtenaySchool of Pharmacy, Queen's University, Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0003-4875-9932
Eneko LarrañetaSchool of Pharmacy, Queen's University, Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0003-3710-0438
Ryan F DonnellySchool of Pharmacy, Queen's University, Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0002-0766-4147

Funding

Engineering and Physical Sciences Research Council 1347368Wellcome Trust WT094085MA.
6 · The paper itself

Abstract

The poor aqueous solubility of existing and emerging drugs is a major issue faced by the pharmaceutical industry. Water-miscible organic solvents, termed co-solvents, can be used to enhance the solubility of poorly soluble substances. Typically, drugs with poor aqueous solubility and Log

Indexed as

atorvastatinFranz cellhydrophobicmicroneedlesNile redolanzapinepoorly solubletransdermal

Identifiers

PMID31766145
PMCPMC6920785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.