Evidence map›Paper›PMID 31766137›Full record

ArticleInternational journal of environmental research and public health2019

Analysis of Toxic Metals in Liquid from Electronic Cigarettes.

Naudia Gray, Mary Halstead, Nathalie Gonzalez-Jimenez, Liza Valentin-Blasini, Clifford Watson, R Steven Pappas

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Naudia GrayCenters for Disease Control and Prevention, Tobacco and Volatiles Branch, 4770 Buford Hwy, MS S110-3, Atlanta, GA 30341, USA.
Mary HalsteadBattelle Analytical Services, 2987 Clairmont Road, Suite 450, Atlanta, GA 30329, USA.
Nathalie Gonzalez-JimenezCenters for Disease Control and Prevention, Tobacco and Volatiles Branch, 4770 Buford Hwy, MS S110-3, Atlanta, GA 30341, USA.
Liza Valentin-BlasiniCenters for Disease Control and Prevention, Tobacco and Volatiles Branch, 4770 Buford Hwy, MS S110-3, Atlanta, GA 30341, USA.
Clifford WatsonCenters for Disease Control and Prevention, Tobacco and Volatiles Branch, 4770 Buford Hwy, MS S110-3, Atlanta, GA 30341, USA.
R Steven PappasCenters for Disease Control and Prevention, Tobacco and Volatiles Branch, 4770 Buford Hwy, MS S110-3, Atlanta, GA 30341, USA.
Centers for Disease Control and Prevention · USBattelle · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the technology of electronic nicotine delivery systems (ENDS), including e-cigarettes, evolves, assessing metal concentrations in liquids among brands over time becomes challenging. A method for quantification of chromium, nickel, copper, zinc, cadmium, tin, and lead in ENDS liquids using triple quadrupole inductively coupled plasma mass spectrometry was developed. The method's limits of detection (LODs) were 0.031, 0.032, 3.15, 1.27, 0.108, 0.099, 0.066 µg/g for Cr, Ni, Cu, Zn, Cd, Sn, and Pb respectively. Liquids analyzed were from different brands and flavors of refill bottles or single-use, rechargeable, and pod devices from different years. Scanning electron microscopy with energy dispersive spectroscopy further evaluated the device components' compositions. Refill liquids before contacting a device were below lowest reportable levels (LRL) for all metals. Copper and zinc were elevated in liquids from devices containing brass. Cadmium was <LRL in all liquids and was not observed in device components. Cr, Ni, Cu, Zn, Sn, and Pb, reported in µg/g, ranged from <LRL to 0.396, 4.04, 903, 454, 0.898, and 13.5 respectively. Elevated metal concentrations in the liquid were also elevated in aerosol from the corresponding device. The data demonstrates the impact of device design and materials on toxic metals in ENDS liquid.

Indexed as

Electronic Nicotine Delivery SystemsVapingAerosolsCadmiumFlavoring AgentsHazardous SubstancesMetals, HeavySpectrometry, X-Ray EmissionAerosolsCadmiumFlavoring AgentsHazardous SubstancesMetals, Heavye-cigaretteselectronic cigarettese-liquidENDSinorganicmetalsvapesvaping

Identifiers

PMID31766137
PMCPMC6888324
OpenAlexW2987507949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.