Evidence map›Paper›PMID 31766001›Full record

ReviewCurrent opinion in virology2019

Reprogramming of cellular metabolic pathways by human oncogenic viruses.

John G Purdy, Micah A Luftig

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. A New Classification Framework to Understand Evolutionary Transitions in Individuality.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Oncogenic Viruses as Entropic Drivers of Cancer Evolution.Frontiers in virology (Lausanne, Switzerland) · 2021
    Article
  14. Metabolic Control by DNA Tumor Virus-Encoded Proteins.Pathogens (Basel, Switzerland) · 2021
    Review
  15. Article
  16. Article
  17. KSHV Reprogramming of Host Energy Metabolism for Pathogenesis.Frontiers in cellular and infection microbiology · 2021
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

John G PurdyDepartment of Immunobiology, BIO5 Institute, University of Arizona, 1657 East Helen St, Keating Bldg Rm424, Tucson, AZ 85719, United States. Electronic address: jgpurdy@email.arizona.edu.
Micah A LuftigDepartment of Molecular Genetics and Microbiology, Duke Center for Virology, Duke University, School of Medicine, 213 Research Dr, DUMC Box 3054, Durham, NC 27710, United States.
Duke University · USUniversity of Arizona · US

Funding

Host pathways regulating Epstein-Barr virus-mediated B cell growth transformationR01CA140337 · NCI · DUKE UNIVERSITY · PI LUFTIG, MICAH ALAN · 2011 to 2025
$5.9M
NCI NIH HHS R01 CA140337
6 · The paper itself

Abstract

Oncogenic viruses, like all viruses, relies on host metabolism to provide the metabolites and energy needed for virus replication. Many DNA tumor viruses and retroviruses will reprogram metabolism during infection. Additionally, some viral oncogenes may alter metabolism independent of virus replication. Virus infection and cancer development share many similarities regarding metabolic reprogramming as both processes demand increased metabolic activity to produce biomass: cell proliferation in the case of cancer and virion production in the case of infection. This review discusses the parallels in metabolic reprogramming between human oncogenic viruses and oncogenesis.

Indexed as

CarcinogenesisCellular ReprogrammingMetabolic Networks and PathwaysBiomassCell ProliferationHepacivirusHepatitis B virusHerpesviridaeHumansMerkel cell polyomavirusNeoplasmsOncogenic VirusesPapillomaviridaeRetroviridaeVirionVirus Replication

Identifiers

PMID31766001
PMCPMC6986357
OpenAlexW2991605375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.