ArticleAmerican journal of respiratory and critical care medicine2020
Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis.
Abstract readComparative Study
In one paragraph
Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 4 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Mucoactive agents in bronchiectasis: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Management of Adult Bronchiectasis: Consensus-Based Guidelines of the German Respiratory Society.Respiration; international review of thoracic diseases · 2026Guideline
- Impact of N-Acetylcysteine on Mucus Hypersecretion in the Airways: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2024Pooled it
- Long-term macrolide treatment for non-cystic fibrosis bronchiectasis in children: a meta-analysis.Scientific reports · 2021Pooled it
- Article
- Treatable traits-based management of bronchiectasis: moving from theory to clinical practice.Chinese medical journal pulmonary and critical care medicine · 2026Review
- Airway mucus plugs in asthma and chronic obstructive pulmonary disease: pathobiology, imaging, and implications for clinical trials.American journal of respiratory and critical care medicine · 2026Review
- Effectiveness of mepolizumab on mucus plugs and clinical outcomes in severe eosinophilic asthma with and without coexisting bronchiectasis: a prospective pilot study.ERJ open research · 2026Article
- Effects of hypertonic saline and/or carbocisteine on sputum rheology in bronchiectasis: CLEAR-EME.ERJ open research · 2026Article
- Association of Chronic Rhinosinusitis andChronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- Use of Recombinant Human Deoxyribonuclease I in Primary Ciliary Dyskinesia Bronchiectasis-A Real Life Pilot Study.Medical sciences (Basel, Switzerland) · 2026Article
- A Quantitative Lung Mucin Score to Identify Chronic Bronchitis.NEJM evidence · 2026Article
- Myeloid cell-specific HMGB1 deficiency exaggerates mucoinflammatory responses but promotes bacterial clearance in mucoinflammatory lung disease.Scientific reports · 2026Article
- High frequency chest wall oscillation for airway clearance in bronchiectasis.Frontiers in rehabilitation sciences · 2026Review
- The convergent pathway of obstructive lung disease: the disease-modifying potential of dipeptidyl peptidase 1 inhibition in COPD, asthma and bronchiectasis overlap.Drugs in context · 2026Review
- Therapies for bronchiectasis: mechanisms and potential effects.Frontiers in immunology · 2026Review
- Airway mucus in infection.Frontiers in physiology · 2026Review
- Research progress on the mechanisms of mucus retention after mycoplasma pneumoniae infection.Frontiers in cellular and infection microbiology · 2026Review
- Inflammatory and Mucociliary Dysfunction-Based Endotypes Across the Spectrum of Chronic Airway Diseases.Chest · 2025Article
- What is the optimal dose of N-acetylcysteine in adult patients with bronchiectasis?-data from the RIBRON registry.Journal of thoracic disease · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
25 authors.
Kathryn A RamseyMarsico Lung Institute.
Alice C H ChenInflammatory Disease Biology and Therapeutics Group, Mater Research Institute, Translational Research Institute, and.
Giorgia RadicioniMarsico Lung Institute.
Rohan LourieInflammatory Disease Biology and Therapeutics Group, Mater Research Institute, Translational Research Institute, and.
Megan MartinDepartment of Respiratory Medicine, Mater Adult Hospital, South Brisbane, Queensland, Australia.
Amy BroomfieldDepartment of Anatomical Pathology, Mater Misericordiae Limited, South Brisbane, Queensland, Australia.
Yong H ShengInflammatory Disease Biology and Therapeutics Group, Mater Research Institute, Translational Research Institute, and.
Sumaira Z HasnainInflammatory Disease Biology and Therapeutics Group, Mater Research Institute, Translational Research Institute, and.
Graham Radford-SmithInflammatory Bowel Diseases Research Laboratory, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.
Lisa A SimmsInflammatory Bowel Diseases Research Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.
Lucy BurrInflammatory Disease Biology and Therapeutics Group, Mater Research Institute, Translational Research Institute, and.
David J ThorntonWellcome Trust Centre for Cell-Matrix Research, Lydia Becker Institute for Immunology and Inflammation, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom; and.ORCID 0000-0001-7148-1970
Simon D BowlerDepartment of Respiratory Medicine, Mater Adult Hospital, South Brisbane, Queensland, Australia.
Stephanie LivengoodMarsico Lung Institute.
Agathe CeppeMarsico Lung Institute.
Michael R KnowlesMarsico Lung Institute.
Peadar G NooneMarsico Lung Institute.
Scott H DonaldsonMarsico Lung Institute.
David B HillMarsico Lung Institute.
Camille EhreMarsico Lung Institute.
Brian ButtonMarsico Lung Institute.
Neil E AlexisCenter for Environmental Medicine, Asthma and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Mehmet KesimerMarsico Lung Institute.
Richard C BoucherMarsico Lung Institute.
Michael A McGuckinInflammatory Disease Biology and Therapeutics Group, Mater Research Institute, Translational Research Institute, and.
Funding
Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Martina Gentzsch · 2004 to 2026
$26.5MThe Biophysics of Mucus Hydration and Adhesion/CohesionP01HL108808 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PEDEN, DAVID B. · 2012 to 2021
$23.9MSynthesis of Effective and Safe Mucolytics for Pulmonary DiseaseUH3HL123645 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2016 to 2018
$4.6MMultiscale Biochemical/Biophysical Integration of Pulmonary Mucus TransportR01HL136961 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2017 to 2020
$3.2MSynthesis of Effective and Safe Mucolytics for Pulmonary DiseaseUH2HL123645 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2014 to 2015
$2.9MNHLBI NIH HHS P01 HL108808NHLBI NIH HHS R01 HL136961NHLBI NIH HHS UH2 HL123645NHLBI NIH HHS UH3 HL123645NIDDK NIH HHS P30 DK065988
Abstract
PubMed holds no abstract for this paper.
Indexed as
AgedBronchiectasisCohort StudiesErythromycinFemaleHumansMaleMiddle AgedMucusQueenslandRespiratory SystemSputumErythromycingene expressioninduced sputummucin
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.