Evidence map›Paper›PMID 31765415›Full record

ArticlePLoS neglected tropical diseases2019

The global burden of trichiasis in 2016.

Rebecca M Flueckiger, Paul Courtright, Mariamo Abdala, Amza Abdou, Zaid Abdulnafea, Tawfik K Al-Khatib, Khaled Amer, Olga Nelson Amiel, Sossinou Awoussi, Ana Bakhtiari and 65 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Infection and immunity · 2025
    Article
  4. Article
  5. bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Article
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  10. Exploring eye care pathways, patient priorities and economics in Pakistan: A scoping review and expert consultation study with thematic analysis.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022
    Article
  11. Trachoma.Nature reviews. Disease primers · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

75 authors.

Rebecca M FlueckigerFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID 0000-0003-4294-2816
Paul CourtrightKilimanjaro Centre for Community Ophthalmology, Division of Ophthalmology, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-0997-347X
Mariamo AbdalaMinisterio da Saude, National Ophthalmology Program, Maputo, Mozambique.
Amza AbdouMinistère de la Santé et de la population, Niamey, Niger.
Zaid AbdulnafeaMinistry of Health, Baghdad, Iraq.
Tawfik K Al-KhatibNational Eye Health Programme, Ministry of Public Health and Population, Sana'a, Yemen.
Khaled AmerMinistry of Health, Cairo, Egypt.
Olga Nelson AmielMinisterio da Saude, Maputo, Mozambique.
Sossinou AwoussiMinistère de la Santé, Lomé, Togo.
Ana BakhtiariThe Task Force for Global Health, Atlanta, GA, USA.
Wilfried BatchoMinistère de la Santé, Cotonou, Benin.
Assumpta Lucienne BellaMinistère de la Santé, Yaoundé, Cameroun.
Kamal Hashim BennawiPrevention of Blindness Program, Khartoum, Sudan.
Simon J BrookerFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Brian K ChuThe Task Force for Global Health, Atlanta, GA, USA.
Michael DejeneMichael Dejene Public Health Consultancy Services, Addis Ababa, Ethiopia.
Djore DezoumbeMinistère de la Santé, N'Djamena, Chad.
Balgesa Elkheir ElshafieTrachoma Control Program, National Ministry of Health, Khartoum, Sudan.
Aba Ange ElvisProgramme National de la Santé Oculaire et de la lutte contre l'Onchocercose, Abidjan, Côte d'Ivoire.
Djouma Nembot FabriceMinistère de la Santé, Yaoundé, Cameroun.
Fatma Juma OmarMinistry of Health, Zanzibar, United Republic of Tanzania.
Missamou FrançoisBureau des Maladies Oculaires, Ministère de la Santé, Kinshasa, Democratic Republic of the Congo.
Drabo FrançoisProgramme national de lutte contre les maladies tropicales négligées (PNMTN), Ouagadougou, Burkina Faso.
Jambi GarapNational Department of Health, Port Moresby, Papua New Guinea.
Michael GichangiMinistry of Health, Nairobi, Kenya.
André GoepoguiProgramme National de Lutte Contre l'Onchocercose et la Cécité et les Maladies Tropicales Négligées, Conakry, Guinea.
Jaouad HammouMinistry of Health, Rabat, Morocco.
Boubacar KadriMinistère de la Santé et de la population, Niamey, Niger.
George KabonaMinistry of Health, Dar es Salaam, United Republic of Tanzania.
Martin Kaborel'unité d'élimination du trachome, PNMTN, Ouagadougou, Burkina Faso.
Khumbo KaluaDepartment of Ophthalmology, University of Malawi, College of Medicine, Blantyre, Malawi.
Mathias KamugishaNational Institute for Medical Research, Dar es Salaam, United Republic of Tanzania.
Biruck KebedeFederal Ministry of Health, Addis Ababa, Ethiopia.
Kaba KeitaProgramme National de Lutte Contre l'Onchocercose et la Cécité et les Maladies Tropicales Négligées, Conakry, Guinea.
Asad Aslam KhanMinistry of Health, Islamabad, Pakistan.
Genet KifluFederal Ministry of Health, Addis Ababa, Ethiopia.
Makoy YibiMinistry of Health, South Sudan.
Garae MacklineMinistry of Health, Port Vila, Vanuatu.
Colin MacleodFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Portia ManangaziraDepartment of Epidemiology and Disease Control, Ministry of Health & Child Welfare, Harare, Zimbabwe.
Michael P MasikaMinistry of Health, Lilongwe, Malawi.
Marilia MassangaieMinisterio da Saude, Department of Neglected Tropical Diseases, Maputo, Mozambique.
Takafira MduluzaDepartment of Biochemistry, University of Zimbabwe, Harare, Zimbabwe.
Nabicassa MenoMinistère de la Santé, Bissau, Guinea-Bissau.
Nicholas MidziDepartment of Medical Microbiology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Abdallahi Ould MinnihMinister de la Sante, Nouakchott, Mauritania.
Sailesh MishraNepal Netra Jyoti Sangh, Kathmandu, Nepal.
Caleb MpyetSightsavers Nigeria, Kaduna, Nigeria & Department of Ophthalmology, Jos University, Jos, Nigeria.
Nicholas MuraguriMinistry of Health, Nairobi, Kenya.
Upendo MwingiraMinistry of Health, Dar es Salaam, United Republic of Tanzania.
Beido NassirouMinistère de la Santé et de la population, Niamey, Niger.
Jean NdjembaBureau des Maladies Oculaires, Ministère de la Santé, Kinshasa, Democratic Republic of the Congo.
Cece NiebaProgramme National de Lutte Contre l'Onchocercose et la Cécité et les Maladies Tropicales Négligées, Conakry, Guinea.
Jeremiah NgondiRTI International, Dar es Salaam, United Republic of Tanzania.ORCID 0000-0003-4357-4816
Nicholas OlobioNigeria Federal Ministry of Health, Abuja, Nigeria.
Alex PavluckRTI International, Washington DC, USA.
Isaac PhiriDepartment of Epidemiology and Disease Control, Ministry of Health & Child Welfare, Harare, Zimbabwe.
Rachel PullanFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Babar QureshiChristian Blind Mission, Bensheim, Germany.
Boubacar SarrMinistère de la santé et de l'Action Sociale, Dakar, Senegal.
Do SeihaPrevention of Blindness Programme, Ministry of Health, Phnom Penh, Cambodia.
Gloria Marina Serrano ChávezMinistry of Health, Guatemala City, Guatemala.
Shekhar SharmaMinistry of Health, Kathmandu, Nepal.
Siphetthavong SisaleumsakNational Ophthalmology Centre, Vientiane, Lao People's Democratic Republic.
Khamphoua SouthisombathNational Program for the Prevention of Blindness, Ministry of Health, Vientiane, Lao People's Democratic Republic.
Gretchen StevensDepartment of Information, Evidence and Research, World Health Organization, Geneva, Switzerland.
Andeberhan Tesfazion WoldendriasDepartment of Public Health, Ministry of Health, Asmara, Eritrea.
Lamine TraoréMinistère de la Santé, Bamako, Mali.
Patrick TuryagumaTrachoma Program, Ministry of Health, Kampala, Uganda.
Rebecca WillisThe Task Force for Global Health, Atlanta, GA, USA.
Georges YayaMinistère de la Santé Publique, Bangui, Central African Republic.
Souleymane YeoProgramme National de la Santé Oculaire et de la lutte contre l'Onchocercose, Abidjan, Côte d'Ivoire.
Francisco ZambroniMinistry of Health, Guatemala City, Guatemala.
Jialiang ZhaoDepartment of Ophthalmology, Peking Union Medical Colllege Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Anthony W SolomonDepartment of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundTrichiasis is present when one or more eyelashes touches the eye. Uncorrected, it can cause blindness. Accurate estimates of numbers affected, and their geographical distribution, help guide resource allocation.

methodsWe obtained district-level trichiasis prevalence estimates in adults for 44 endemic and previously-endemic countries. We used (1) the most recent data for a district, if more than one estimate was available; (2) age- and sex-standardized corrections of historic estimates, where raw data were available; (3) historic estimates adjusted using a mean adjustment factor for districts where raw data were unavailable; and (4) expert assessment of available data for districts for which no prevalence estimates were available.

findingsInternally age- and sex-standardized data represented 1,355 districts and contributed 662 thousand cases (95% confidence interval [CI] 324 thousand-1.1 million) to the global total. Age- and sex-standardized district-level prevalence estimates differed from raw estimates by a mean factor of 0.45 (range 0.03-2.28). Previously non- stratified estimates for 398 districts, adjusted by ×0.45, contributed a further 411 thousand cases (95% CI 283-557 thousand). Eight countries retained previous estimates, contributing 848 thousand cases (95% CI 225 thousand-1.7 million). New expert assessments in 14 countries contributed 862 thousand cases (95% CI 228 thousand-1.7 million). The global trichiasis burden in 2016 was 2.8 million cases (95% CI 1.1-5.2 million).

interpretationThe 2016 estimate is lower than previous estimates, probably due to more and better data; scale-up of trichiasis management services; and reductions in incidence due to lower active trachoma prevalence.

Indexed as

Global HealthAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPrevalenceTrichiasisYoung Adult

Identifiers

PMID31765415
PMCPMC6901231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.