ArticleJournal of pediatric gastroenterology and nutrition2019
Polyp Characteristics of Nonsyndromic and Potentially Syndromic Juvenile Polyps: A Retrospective Cohort Analysis.
Article in Journal of pediatric gastroenterology and nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Food-sensitized children with juvenile colorectal polyps exhibit a distinct mucosal and fecal microbial signature associated with inflammation.Scientific reports · 2026Article
- Clinicopathological Characteristics and Synchronous Lesions in Colorectal Cancer: A Single-Center Retrospective Colonoscopy Study.Journal of clinical medicine · 2025Article
- A Rare Presentation of Juvenile Rectal Polyps in an Adolescent Male With Rectal Bleeding: A Case Report.Cureus · 2025Article
- Endoscopic features of solitary colorectal hamartomatous polyps: Solitary juvenile polyp and Peutz-Jeghers polyp.Endoscopy international open · 2025Article
- Studying the Effect of the Host Genetic Background of Juvenile Polyposis Development Using Collaborative Cross andInternational journal of molecular sciences · 2024Article
- A case report of a giant solitary juvenile polyp: from obstructed defecation syndrome to incontinence.Annals of coloproctology · 2024Article
- An Unexpected Diagnosis of The Rectal Polyp: Perivascular Epithelioid Cell Tumor.Turkish archives of pediatrics · 2024Article
- Single-cell landscape of the cellular microenvironment in three different colonic polyp subtypes in children.Clinical and translational medicine · 2024Article
- Cancer risk and mortality in patients with solitary juvenile polyps-A nationwide cohort study with matched controls.United European gastroenterology journal · 2023Article
- Associations of Polyp Characteristics in Children and Adolescents Presenting with Less Than Five Colorectal Polyps: A Full Colonoscopy Is Still Required.Gut and liver · 2023Article
- Practice Patterns of Colorectal Polypectomy in Pediatric Endoscopic Specialists in South Korea: A Nationwide Survey Study.Pediatric gastroenterology, hepatology & nutrition · 2023Article
- Can a Solitary Juvenile Polyp Be Regarded as a Nonmalignant Polyp?ACG case reports journal · 2022Article
- [Clinical features of intestinal polyps and risk factors for secondary intussusception in children: an analysis of 2 669 cases].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Characteristics and potential malignancy of colorectal juvenile polyps in adults: a single-center retrospective study in China.BMC gastroenterology · 2022Article
- Inflammatory cloacogenic polyps in children: diagnostic yield of rectal retroflexion during colonoscopy.BMC gastroenterology · 2022Article
- Colocolic Intussusception in Children: A Case Series and Review of the Literature.Frontiers in surgery · 2022Article
- The management of colonic polyps in children: a 13-year retrospective study.European journal of pediatrics · 2021Article
- Polypoid disease of colon in children.Pediatric surgery international · 2020Review
- Secondary Colo-Colic Intussusception Caused by Giant Polyp of Sigmoid Colon in a 5-Year-Old Girl.Case reports in gastroenterologyArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundJuvenile polyps (JPs) are the most common gastrointestinal polyps diagnosed in children. There is paucity of evidence differentiating polyp burden groups and the presence and significance of neoplastic changes.
methodsA retrospective chart review of patients, ages birth through 18 years with nonsyndromic JPs was performed from 2003 to 2017. Abstracted data included basic demographics, age, clinical presentation, colonoscopy findings, and pathology report. Slides of polyps with neoplasia were reviewed by a pathologist.
resultsA total of 213 subjects underwent 326 procedures and 435 polypectomies. Subjects with positive family history, positive gene mutations, or numerous (>10) polyps were excluded. Groups were defined by polyp number (1, 2-4, 5-10). Polyp recurrence on repeat colonoscopy was significantly related to polyp burden (1 polyp: 1.5%/2-4 polyps 19.2%/5-10 polyps 82.6%: P < 0.001). Polyp distribution was significantly different amongst different groups with isolated polyps favoring a distal distribution. JPs harboring adenomatous foci were reported in 26 (12%) patients. JPs harboring adenomatous foci were significantly more likely to be proximally distributed but the presence of adenomatous transformation within the polyps did not correlate with polyp number or the likelihood of polyp recurrence on repeat colonoscopy.
conclusionsJP recurrence is positively and significantly related to polyp burden. JP harbored adenomatous changes independent of polyp number, underscoring a possible malignant potential in JPs. In the absence of a consistent genotype or pedigree, the presence of adenomatous transformation within JPs cannot be construed as a biomarker for syndromic juvenile polyposis.
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