Evidence map›Paper›PMID 31765299›Full record

ArticleIEEE transactions on bio-medical engineering2020

Miniaturized Intracavitary Forward-Looking Ultrasound Transducer for Tissue Ablation.

Howuk Kim, Huaiyu Wu, Namwoo Cho, Pei Zhong, Kamran Mahmood, Herbert Kim Lyerly, Xiaoning Jiang

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Dual-Frequency Intravascular Sonothrombolysis: An In Vitro Study.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Howuk Kim
Huaiyu Wu
Namwoo Cho
Pei Zhong
Kamran Mahmood
Herbert Kim Lyerly
Xiaoning Jiang
North Carolina State University · USDuke University · US

Funding

Integrated Dual-frequency Ultrasound Catheter for Accelerated Sonothrombolysis (iDUCAS)R01HL141967 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Xiaoning Jiang, Zhen Xu · 2018 to 2026
$4.1M
NHLBI NIH HHS R01 HL141967
6 · The paper itself

Abstract

objectiveThis paper aims to develop a miniaturized forward-looking ultrasound transducer for intracavitary tissue ablation, which can be used through an endoscopic device. The internal ultrasound (US) delivery is capable of directly interacting with the target tumor, resolving adverse issues of currently available US devices, such as unintended tissue damage and insufficient delivery of acoustic power.

methodsTo transmit a high acoustic pressure from a small aperture (<3 mm), a double layer transducer (1.3 MHz) was designed and fabricated based on numerical simulations. The electric impedance and the acoustic pressure of the actual device was characterized with an impedance analyzer and a hydrophone. Ex vivo tissue ablation tests and temperature monitoring were then conducted with porcine livers.

resultsThe acoustic intensity of the transducer was 37.1 W/cm

conclusionThis miniaturized US transducer is a promising medical option for the precise tissue ablation, which can reduce the risk of unintended tissue damage found in noninvasive US treatments. SIGNIFICANCE: Having a small aperture (2 mm), the intracavitary device is capable of ablating a bio tissue in 5 min with a relatively low electric power (<17 W).

Indexed as

High-Intensity Focused Ultrasound AblationUltrasonic TherapyAcousticsAnimalsSwineTemperatureTransducersUltrasonography

Identifiers

PMID31765299
PMCPMC7269183
OpenAlexW2990089564

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.