Evidence map›Paper›PMID 31765130›Full record

ArticleAnalytical chemistry2020

Enhanced Characterization of Membrane Protein Complexes by Ultraviolet Photodissociation Mass Spectrometry.

Sarah N Sipe, John W Patrick, Arthur Laganowsky, Jennifer S Brodbelt

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 41 citations in OpenAlex.

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  9. Top-down proteomics.Nature reviews. Methods primers · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sarah N SipeDepartment of Chemistry , University of Texas at Austin , Austin , Texas 78712 , United States.
John W PatrickDepartment of Chemistry , Texas A&M University , College Station , Texas 77842 , United States.
Arthur LaganowskyDepartment of Chemistry , Texas A&M University , College Station , Texas 77842 , United States.ORCID 0000-0001-5012-5547
Jennifer S BrodbeltDepartment of Chemistry , University of Texas at Austin , Austin , Texas 78712 , United States.ORCID 0000-0003-3207-0217
Texas A&M University · USThe University of Texas at Austin · US

Funding

Native ion mobility mass spectrometry studies of potassium inward rectifier channels: insight into gating and lipid bindingDP2GM123486 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI LAGANOWSKY, ARTHUR D · 2016 to 2016
$2.2M
UVPD Mass Spectrometry of Protein ComplexesR01GM121714 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI BRODBELT, JENNIFER S. · 2017 to 2020
$1.4M
NIGMS NIH HHS DP2 GM123486NIGMS NIH HHS R01 GM121714
6 · The paper itself

Abstract

Development of chemical chaperones to solubilize membrane protein complexes in aqueous solutions has allowed for gas-phase analysis of their native-like assemblies, including rapid evaluation of stability and interacting partners. Characterization of protein primary sequence, however, has thus far been limited. Ultraviolet photodissociation (UVPD) generates a multitude of sequence ions for the

Indexed as

Amino Acid SequenceAquaporinsCation Transport ProteinsEscherichia coliEscherichia coli ProteinsIon ChannelsMass SpectrometryModels, MolecularPhotolysisProtein Processing, Post-TranslationalUltraviolet RaysAmtB protein, E coliaqpZ protein, E coliAquaporinsCation Transport ProteinsEscherichia coli ProteinsIon ChannelsMscL protein, E coli

Identifiers

PMID31765130
PMCPMC6949371
OpenAlexW2990475748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.