Evidence map›Paper›PMID 31764804›Full record

ArticleMedicine2019

Study on the treatment of pancreatic cancer with integrated traditional Chinese and Western medicine: A study protocol of a multicenter prospective cohort study.

Juling Jiang, Rui Liu, Zhenhua Zhang, Xiwen Zhang, Runzhi Qi, Shuntai Chen, Xing Zhang, Yupeng Xi, Qiujun Guo, Honggang Zheng and 1 more

Abstract read
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Frontiers in pharmacology · 2024
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juling JiangGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Rui LiuGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Zhenhua ZhangBeijing University of Chinese Medicine, Beijing, China.
Xiwen ZhangGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Runzhi QiGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Shuntai ChenBeijing University of Chinese Medicine, Beijing, China.
Xing ZhangGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Yupeng XiGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Qiujun GuoGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Honggang ZhengGuang'anmen Hospital, China Academy of Chinese Medical Sciences.
Baojin HuaGuang'anmen Hospital, China Academy of Chinese Medical Sciences.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPancreatic cancer is one of the most lethal malignancies worldwide. Most patients are diagnosed at an advanced stage, which leads to a poor prognosis and a low survival rate. At present, treatment options for pancreatic cancer are limited, so it is vital to explore new treatments and strategies. Traditional Chinese medicine (TCM) is an important method for cancer prevention and treatment in China. We will conduct a multicenter, prospective cohort study to evaluate the survival and quality of life of patients with advanced pancreatic cancer treated with integrated traditional Chinese and Western medicine, further refine the core pathogenesis of TCM for pancreatic cancer, form a core prescription, and provide clinical data support for the clinical plan of integrated treatment of pancreatic cancer using Chinese and Western medicine; this will aid in the development of the best comprehensive treatment plan for patients. METHODS AND ANALYSIS: This study will recruit patients with stage 3 to 4 pancreatic cancer in 12 medical units from April 2019 to June 2020. Patients will be divided into a Western medicine treatment group and an integrated traditional Chinese and Western medicine treatment group, with a total of 148 patients. Overall survival is the main efficacy index, while the secondary efficacy indexes are progression-free survival, tumor markers, TCM symptom grading scale, quality of life assessment, Eastern Cooperative Oncology Group (ECOG) score, and imaging assessment. A follow-up will be performed every 6 weeks ±1 week. The end point is the death of the patient or the end of the study (October 31, 2021). Statistical analysis will be performed using Statistical Packages of Social Sciences software (SPSS). ETHICS AND DISSEMINATION: This work was supported by Beijing Municipal Science and Technology Commission and approved by the ethics committee of Guang'anmen Hospital, China Academy of Chinese Medical Sciences (Approval No. 2019-016-KY). All patients will sign a written informed consent prior to data collection. The results will be disseminated through peer-reviewed journals and conference presentations and will be openly shared after completion of the trial.

trial registrationThe trial was registered with the Chinese Clinical Trials Registry (ChiCTR1900022632, pre-registration).

Indexed as

Medicine, Chinese TraditionalMulticenter Studies as TopicProspective StudiesResearch DesignCohort StudiesCombined Modality TherapyHumansPancreatic Neoplasms

Identifiers

PMID31764804
PMCPMC6882619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.