Observational studyJournal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases2019
The Montreal Cognitive Assessment Test: A Useful Tool in Screening of Cognitive Impairment in Patients With Systemic Lupus Erythematosus.
Observational study in Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Cognitive Screening and Neuropsychological Evaluation in Children and Young Adults With Childhood-Onset Systemic Lupus Erythematosus: A Survey of Rheumatologists.ACR open rheumatology · 2026Article
- Cognitive dysfunction in pediatric systemic lupus erythematosus: current knowledge and future directions.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2024Review
- Clinical associations of cognitive dysfunction in systemic lupus erythematosus.Lupus science & medicine · 2023Article
- Comparison of DBFS with MoCA and MMSE tools for MCI screening.Bioinformation · 2023Article
- Absence of association between nailfold capillary findings and mild cognitive dysfunction in systemic lupus erythematosus.Clinical rheumatology · 2022Article
- Evaluation of the Montreal Cognitive Assessment as a screening tool for cognitive dysfunction in SLE.Lupus science & medicine · 2021Article
- Article
- Comparison of the Impact of Zika and Dengue Virus Infection, and Other Acute Illnesses of Unidentified Origin on Cognitive Functions in a Prospective Cohort in Chiapas Mexico.Frontiers in neurology · 2021Article
- Some like it, some do not: behavioral responses and central processing of olfactory-trigeminal mixture perception.Brain structure & function · 2021Article
- Mental disorders in systemic lupus erythematosus: a cohort study.Rheumatology international · 2019Article
- Cognitive Dysfunction in Systemic Lupus Erythematosus: A Case for Initiating Trials.Arthritis & rheumatology (Hoboken, N.J.) · 2019Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectiveSystemic lupus erythematosus (SLE) is an inflammatory, chronic, and multisystemic disease, which may be associated with a wide range of neuropsychiatric manifestations, including cognitive impairment. Cognitive evaluations based on screening tests might identify early SLE-related cognitive alterations. The aim of this study was to evaluate and to compare the efficacy of three screening tests (Montreal Cognitive Assessment [MoCA], Mini Mental State Examination [MMSE], Cognitive Symptom Inventory [CSI]) against the gold standard (neuropsychological battery), in order to identify the most efficient screening test for cognitive impairment in patients with SLE.
methodsThis observational cross-sectional study recruited 44 patients, from August to December 2017, who were diagnosed with SLE according to the Systemic Lupus International Collaborating Clinics (SLICC) Criteria 2012, and had no medical or psychiatric comorbidities. The patients were evaluated using the MoCA, MMSE, CSI, and the gold standard. Spearman's correlation and area under the curve analysis were performed; p < 0.05 was considered significant.
resultsThe MoCA test showed the highest correspondence with the gold standard (AUC = 99.4%, p < 0.001), sensitivity (84%), and specificity (100%). This was followed by the MMSE (AUC = 92.6%, p < 0.001; sensitivity, 54.8%; specificity, 100%) and the CSI (AUC = 30.6%, p < 0.05; sensitivity, 54.8%; specificity, 30.76%).
conclusionThe MoCA is a brief, easily applied screening test that is highly effective for detecting cognitive impairment in SLE patients. It could be useful in clinical follow-up as a tool for early detection of cognitive alterations.
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