Evidence map›Paper›PMID 31763785›Full record

ArticleCurrent protocols in protein science2019

NMR Spectroscopy-Based Metabolic Profiling of Biospecimens.

Arjun Sengupta, Aalim M Weljie

Abstract read
In one paragraph

Article in Current protocols in protein science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Circadian and Sleep Metabolomics Across Species.Journal of molecular biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arjun SenguptaDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Aalim M WeljieDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Trevor M Penning · 2006 to 2026
$35.3M
UPR, interferon signaling and tumorigenesisP01CA165997 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DIEHL, JOHN ALAN · 2013 to 2023
$10.9M
Metabolomics of obstructive sleep apneaR01HL142981 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WELJIE, AALIM M · 2020 to 2023
$4.4M
Balance of sleep and circadian metabolic switches in DrosophilaR01DK120757 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SEHGAL, AMITA, WELJIE, AALIM M · 2019 to 2022
$2.1M
Determining and enhancing metabolite fitness for metabolomics measurementsR21CA213234 · NCI · UNIVERSITY OF PENNSYLVANIA · PI WELJIE, AALIM M · 2017 to 2019
$626k
Forgetting to sleep: metabolic consequences of sleep loss and associated neurocognitive deficitsR21AG052905 · NIA · UNIVERSITY OF PENNSYLVANIA · PI WELJIE, AALIM M · 2017 to 2018
$443k
NCI NIH HHS P01 CA165997NCI NIH HHS R21 CA213234NHLBI NIH HHS R01 HL142981NIA NIH HHS R21 AG052905NIDDK NIH HHS R01 DK120757NIEHS NIH HHS P30 ES013508
6 · The paper itself

Abstract

Metabolomics refers to study of metabolites in biospecimens such as blood serum, tissues, and urine. Nuclear magnetic resonance (NMR) spectroscopy and ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS; mass spectrometry coupled with liquid chromatography) are most frequently employed to analyze complex biological/clinical samples. NMR is a relatively insensitive tool compared to UPLC-MS/MS but offers straightforward quantification and identification and easy sample processing. One-dimensional

Indexed as

MetabolomeHumansMagnetic Resonance SpectroscopyMetabolomicsPlasmaSerummetabolitesmetabolomicsNMRtargeted profiling

Identifiers

PMID31763785
PMCPMC6884008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.