Evidence map›Paper›PMID 31763739›Full record

ReviewJournal of magnetic resonance imaging : JMRI2020

Deep Learning for Lesion Detection, Progression, and Prediction of Musculoskeletal Disease.

Richard Kijowski, Fang Liu, Francesco Caliva, Valentina Pedoia

Open access · greenAbstract readReview
In one paragraph

Review in Journal of magnetic resonance imaging : JMRI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Detection of maxillary sinus pathologies using deep learning algorithms.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Artificial intelligence in musculoskeletal applications: a primer for radiologists.Diagnostic and interventional radiology (Ankara, Turkey) · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Richard KijowskiDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-2669-267X
Fang LiuDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0001-8032-6681
Francesco CalivaDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Valentina PedoiaDepartment of Radiology, University of California at San Francisco School of Medicine, San Francisco, California, USA.
University of Wisconsin–Madison · USUniversity of California, San Francisco · US

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Kira Grogg · 2017 to 2026
$14.8M
Structural, Biochemical and Functional Connectivity in Osteoarthritis using Quantitative Magnetic Resonance Imaging and Skeletal BiomechanicsR01AR069006 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA, SOUZA, RICHARD BRIAN · 2016 to 2025
$7.2M
Quantitative Oncologic PET-MRR01CA165221 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2012 to 2023
$4.7M
Ultra-Fast Knee MRI with Deep LearningR01AR078762 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA · 2021 to 2025
$2.8M
Multi-component T2 and T2* mapping of All Water Components of Articular CartilageR01AR068373 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI KIJOWSKI, RICHARD · 2015 to 2018
$1.4M
Deep Learning for Characterizing Knee Joint Degeneration Predicting Progression of Osteoarthritis and Total Knee ReplacementR61AR073552 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA, PEDOIA, VALENTINA · 2018 to 2019
$871k
Multidimensional MRI-based Non-Euclidean Deep Learning to Study OsteoarthritisR00AR070902 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PEDOIA, VALENTINA · 2018 to 2020
$747k
NCI NIH HHS R01 CA165221NIAMS NIH HHS R00 AR070902NIAMS NIH HHS R01 AR068373NIAMS NIH HHS R01 AR078762NIAMS NIH HHS R61 AR073552NIBIB NIH HHS P41 EB022544
6 · The paper itself

Abstract

Deep learning is one of the most exciting new areas in medical imaging. This review article provides a summary of the current clinical applications of deep learning for lesion detection, progression, and prediction of musculoskeletal disease on radiographs, computed tomography (CT), magnetic resonance imaging (MRI), and nuclear medicine. Deep-learning methods have shown success for estimating pediatric bone age, detecting fractures, and assessing the severity of osteoarthritis on radiographs. In particular, the high diagnostic performance of deep-learning approaches for estimating pediatric bone age and detecting fractures suggests that the new technology may soon become available for use in clinical practice. Recent studies have also documented the feasibility of using deep-learning methods for identifying a wide variety of pathologic abnormalities on CT and MRI including internal derangement, metastatic disease, infection, fractures, and joint degeneration. However, the detection of musculoskeletal disease on CT and especially MRI is challenging, as it often requires analyzing complex abnormalities on multiple slices of image datasets with different tissue contrasts. Thus, additional technical development is needed to create deep-learning methods for reliable and repeatable interpretation of musculoskeletal CT and MRI examinations. Furthermore, the diagnostic performance of all deep-learning methods for detecting and characterizing musculoskeletal disease must be evaluated in prospective studies using large image datasets acquired at different institutions with different imaging parameters and different imaging hardware before they can be implemented in clinical practice. LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY STAGE: 2 J. MAGN. RESON. IMAGING 2020;52:1607-1619.

Indexed as

Deep LearningMusculoskeletal DiseasesChildHumansMagnetic Resonance ImagingProspective StudiesTomography, X-Ray Computeddeep leaningimagingmusculoskeletalreview

Identifiers

PMID31763739
PMCPMC7251925
OpenAlexW2990070310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.