ArticleACS omega2019
Design of a Helical-Stabilized, Cyclic, and Nontoxic Analogue of the Peptide Cm-p5 with Improved Antifungal Activity.
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Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
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Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Natural and Synthetic AMPs from Latin America across Diversity Engineering and Applications.ACS infectious diseases · 2026Review
- Cm-p5, a synthetic antimicrobial peptide shows anti-Trypanosoma cruzi activity.PLoS neglected tropical diseases · 2026Article
- Anti-biofilm peptides can rescue fluconazole and amphotericin B efficacies against Candida albicans.Scientific reports · 2025Article
- Synthesis of Cyclic Hexapeptides via the Hydrazide Method and Evaluation of Their Antibacterial Activities.Molecules (Basel, Switzerland) · 2025Article
- Improvement of the Antimicrobial Peptide Activity by Means of Chitosan-Based Nanoparticles.Biotechnology journal · 2025Article
- Structural Characterization of the Dimers and Selective Synthesis of the Cyclic Analogues of the Antimicrobial Peptide Cm-p5.Antibiotics (Basel, Switzerland) · 2025Article
- dsAMP and dsAMPGAN: Deep Learning Networks for Antimicrobial Peptides Recognition and Generation.Antibiotics (Basel, Switzerland) · 2024Article
- Current Perspectives of Antifungal Therapy: A Special Focus onJournal of fungi (Basel, Switzerland) · 2024Review
- The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human PathogenPharmaceuticals (Basel, Switzerland) · 2024Article
- Pore-forming peptide C14R exhibits potent antifungal activity against clinical isolates ofFrontiers in cellular and infection microbiology · 2024Article
- Inhibition of Pertussis Toxin by Human α-Defensins-1 and -5: Differential Mechanisms of Action.International journal of molecular sciences · 2023Article
- Cm-p5 Peptide Dimers Inhibit Biofilms ofInternational journal of molecular sciences · 2023Article
- Fungicidal activity of human antimicrobial peptides and their synergistic interaction with common antifungals against multidrug-resistant Candida auris.International microbiology : the official journal of the Spanish Society for Microbiology · 2023Article
- Aptamers as Novel Binding Molecules on an Antimicrobial Peptide-Armored Composite Hydrogel Wound Dressing for Specific Removal and Efficient Eradication ofInternational journal of molecular sciences · 2023Article
- Review
- ABP-Finder: A Tool to Identify Antibacterial Peptides and the Gram-Staining Type of Targeted Bacteria.Antibiotics (Basel, Switzerland) · 2022Article
- Small molecules for combating multidrug-resistant superbugActa pharmaceutica Sinica. B · 2022Review
- Article
- Emerging and future strategies in the management of recalcitrant Candida auris.Medical mycology · 2022Review
- Antimicrobial Peptides: From Design to Clinical Application.Antibiotics (Basel, Switzerland) · 2022Review
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Authors and funding
20 authors at 7 institutions in 4 countries.
Fidel E Morales VicenteGeneral Chemistry Department, Faculty of Chemistry and Center for Natural Products Research, Faculty of Chemistry, University of Havana, Zapata y G, 10400 La Habana, Cuba.
Melaine González-GarciaCenter for Protein Studies, Faculty of Biology, University of Havana, 25 and I, 10400 La Habana, Cuba.
Erbio Diaz PicoSynthetic Peptides Group, Center for Genetic Engineering and Biotechnology, P.O. Box 6162, 10600 La Habana, Cuba.
Elena Moreno-CastilloGeneral Chemistry Department, Faculty of Chemistry and Center for Natural Products Research, Faculty of Chemistry, University of Havana, Zapata y G, 10400 La Habana, Cuba.
Hilda E GaraySynthetic Peptides Group, Center for Genetic Engineering and Biotechnology, P.O. Box 6162, 10600 La Habana, Cuba.
Pablo E RosiDepartment of Inorganic Chemistry, Analytical and Physical Chemistry, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires C1428EGA, Argentina.
Asiel Mena JimenezGeneral Chemistry Department, Faculty of Chemistry and Center for Natural Products Research, Faculty of Chemistry, University of Havana, Zapata y G, 10400 La Habana, Cuba.
Jose A Campos-DelgadoCenter of Excellence for Research in Sustainable Chemistry (CERSusChem), Department of Chemistry, Federal University of São Carlos-UFSCar, São Paulo 13565-905, Brazil.
Daniel G RiveraGeneral Chemistry Department, Faculty of Chemistry and Center for Natural Products Research, Faculty of Chemistry, University of Havana, Zapata y G, 10400 La Habana, Cuba.
Glay ChineaSynthetic Peptides Group, Center for Genetic Engineering and Biotechnology, P.O. Box 6162, 10600 La Habana, Cuba.
Rosemeire C L R PietroLaboratory of Pharmaceutical Biotechnology, Department of Drugs and Medicines, School of Pharmaceutical Sciences, UNESP, Araraquara 14800-900, Brazil.
Steffen StengerInstitute of Medical Microbiology and Hygiene, University Clinic of Ulm, Robert Koch Str. 8, Ulm D-89081, Germany.
Barbara SpellerbergInstitute of Medical Microbiology and Hygiene, University Clinic of Ulm, Robert Koch Str. 8, Ulm D-89081, Germany.
Dennis KubiczekInstitute of Pharmaceutical Biotechnology, Ulm University, James-Frank-Ring N27, 89081 Ulm, Germany.
Nicholas BodenbergerInstitute of Pharmaceutical Biotechnology, Ulm University, James-Frank-Ring N27, 89081 Ulm, Germany.
Steffen DietzInstitute of Pharmaceutical Biotechnology, Ulm University, James-Frank-Ring N27, 89081 Ulm, Germany.
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, James-Frank-Ring N27, 89081 Ulm, Germany.
Márcio Weber PaixãoCenter of Excellence for Research in Sustainable Chemistry (CERSusChem), Department of Chemistry, Federal University of São Carlos-UFSCar, São Paulo 13565-905, Brazil.
Ludger StändkerCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), University Ulm, Faculty of Medicine, Ulm University, 89081 Ulm, Germany.
Anselmo J Otero-GonzálezCenter for Protein Studies, Faculty of Biology, University of Havana, 25 and I, 10400 La Habana, Cuba.
Universität Ulm · DEUniversity of Havana · CUCentro de Ingeniería Genética y Biotecnología · CUUniversidade Federal de São Carlos · BRInstitute of Medical Microbiology and Hygiene · DEUniversidad de Buenos Aires · ARUniversidade Estadual Paulista (Unesp) · BR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following the information obtained by a rational design study, a cyclic and helical-stabilized analogue of the peptide Cm-p5 was synthetized. The cyclic monomer showed an increased activity in vitro against
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.