Evidence map›Paper›PMID 31763181›Full record

ArticleToxicology reports2019

Toxicity of polycyclic aromatic hydrocarbons involves NOX2 activation.

Joycelyn Smith, Rajendra Neupane, William McAmis, Udai Singh, Saurabh Chatterjee, Samir Raychoudhury

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Joycelyn SmithDepartment of Biology, Chemistry, and Environmental Health Science, Benedict College, 1600 Harden Street, Columbia, SC, 29204, USA.
Rajendra NeupaneDepartment of Biology, Chemistry, and Environmental Health Science, Benedict College, 1600 Harden Street, Columbia, SC, 29204, USA.
William McAmisDepartment of Biology, Chemistry, and Environmental Health Science, Benedict College, 1600 Harden Street, Columbia, SC, 29204, USA.
Udai SinghSchool of Medicine, University of South Carolina, Columbia, SC, USA.
Saurabh ChatterjeeEnvironmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Samir RaychoudhuryDepartment of Biology, Chemistry, and Environmental Health Science, Benedict College, 1600 Harden Street, Columbia, SC, 29204, USA.
Benedict College · USSouth Carolina Department of Health and Environmental Control · USUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycyclic Aromatic Hydrocarbons (PAHs) are environmental pollutants. The present study compares the toxic effects of BaP alone and a mixture of PAHs on human breast cancer cells. We hypothesize that PAH mixture is more toxic than BaP alone, and an increased NOX2 activation is related to PAH-induced oxidative stress. Initially, we exposed cultured human breast cancer cells to BaP alone (125 ng/mL and 500 ng/mL) and a mixture of PAHs (125 ng/mL and 500 ng/mL). After 24 h of exposure, the PAH mixture demonstrated a significant (

Indexed as

Benzo[a]pyreneFlow cytometryNOX2Polycyclic aromatic hydrocarbonsToxicity

Identifiers

PMID31763181
PMCPMC6861563
OpenAlexW2985438685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.