ReviewJournal of clinical & translational endocrinology2020
Graves' disease and mental disorders.
Review in Journal of clinical & translational endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06293534 (Thyroid Dysfunction in Patient With Major Psychiatric Disorders Admitted to Psychiatric Unit of Assiut University Hospital), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Thyroid Dysfunction in Patient With Major Psychiatric Disorders Admitted to Psychiatric Unit of Assiut University Hospital
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- What is the impact of stress on the onset and anti-thyroid drug therapy in patients with graves' disease: a systematic review and meta-analysis.BMC endocrine disorders · 2023Pooled it
- Mitral valve regurgitation and emotional dysregulation secondary to long-standing Graves' thyrotoxicosis.Endocrinology, diabetes & metabolism case reports · 2026Article
- Associations between thyroid hormones and biochemical metabolism in major depressive disorder patients with and without comorbid eating disorders.Eating and weight disorders : EWD · 2026Article
- HPT Axis Dysregulation in Mood and Anxiety Disorders: The Clinical Utility of Routine Hormonal Dosing in Psychiatric In-Patients.Diseases (Basel, Switzerland) · 2026Article
- Cultural Determinants of Chronic Disease Management: A Cross-Comparative Medical Review.Healthcare (Basel, Switzerland) · 2026Review
- Plant-derived nutritional components in thyroid disease-related neuropsychiatric disorders: mechanistic insights and advances.Frontiers in nutrition · 2026Review
- Psychosis as the Initial and Main Presentation of Graves' Disease: A Case Report from Saudi Arabia.Cureus · 2025Article
- Effects of depression on thyroid function, pathology and ultrasonography in rats.Journal of molecular histology · 2025Article
- Article
- Article
- The impact of COVID-19 on thyroid function and psychological state of Graves' disease: a one-year prospective study.Frontiers in endocrinology · 2025Article
- Nomogram Prediction Model of Thyroid Nodule in Healthcare Professionals: Based on Physical and Psychological Risk Factors.Risk management and healthcare policy · 2025Article
- Non-linear relationship between TSH and psychotic symptoms on first episode and drug naïve major depressive disorder patients: a large sample sized cross-sectional study in China.BMC psychiatry · 2024Article
- Psychiatric complications in Graves' disease.European thyroid journal · 2024Article
- Prevalence and Related Factors of Thyroid Nodules in Physical Examination Population in a Level-A Hospital in Jinan.Journal of multidisciplinary healthcare · 2024Article
- Stress-Induced Graves Disease: Spontaneous Recovery After Stress Relief.Journal of the Endocrine Society · 2023Article
- Article
- Adaptation and validation of the Hungarian version of Thyroid-Related Patient-Reported Outcome-39 (ThyPro-39) questionnaire: testing factor structure, known-group validity with the comparison of quality of life in Hashimoto's thyroiditis and Graves' disease.Journal of patient-reported outcomes · 2023Article
- Article
- Prediction for recurrence following antithyroid drug therapy for Graves' hyperthyroidism.Archives of endocrinology and metabolism · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mental disorders merge highly with thyroid diseases. Because of its regulatory effects on serotonin and noradrenalin, T3 has been linked closely to depression and anxiety. It has known that in many cases, the mental symptoms persist even after normalization of thyroid function by treatment. Psychosocial factors including stress have been associated with mental symptoms even after thyroid function normalization in Graves' disease and a combination of mental disorders have been related to the exacerbation of hyperthyroidism. These findings suggest that psychosomatic approaches based on the bio-psycho-social medical model are important for the treatment of mental disorders associated with Graves' disease.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.