Evidence map›Paper›PMID 31763058›Full record

ArticleAmerican journal of cardiovascular disease2019

Preclinical cardiac disease in nonalcoholic fatty liver disease with and without metabolic syndrome.

Jasbir Makker, Hassan Tariq, Jonathan N Bella, Kishore Kumar, Chukwunonso Chime, Harish Patel, Muhammad Umar Kamal, Danial Shaikh, Vamshidhar Vootla, Bharat Bajantri and 5 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cardiovascular disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Assessment of left atrial function by two-dimensional speckle tracking echocardiography in patients with metabolic-associated fatty liver disease.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Article
  3. Extracellular Vesicles and Fatty Liver.Advances in experimental medicine and biology · 2023
    Review
  4. Article
  5. Nonalcoholic Fatty Liver Disease (NAFLD) Name Change: Requiem or Reveille?Journal of clinical and translational hepatology · 2021
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Jasbir MakkerBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Hassan TariqBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Jonathan N BellaBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Kishore KumarBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Chukwunonso ChimeBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Harish PatelBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Muhammad Umar KamalBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Danial ShaikhBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Vamshidhar VootlaBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Bharat BajantriBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Umut GomceliBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Mohammad AlshellehBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Richard PeraltaBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Aiyi ZhangBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Sridhar ChilimuriBronx Care Health System, Department of Medicine Bronx, NY 10457, USA.
Montefiore Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic syndrome is associated with preclinical cardiac disease and nonalcoholic fatty liver disease (NAFLD). It is uncertain whether preclinical cardiac disease is present in patients with NAFLD without metabolic syndrome (MetS).

objectiveTo explore preclinical cardiac disease in patients with NAFLD.

methodsA total of 64 patients with NAFLD, based on computed tomography scans liver attenuation, were identified. A control group, matched to age and gender, comprising of 94 patients was also drafted. Finally, two additional groups of patients with metabolic syndrome, with (n = 40) and without (n = 74) NAFLD, were also identified. Patients with hypertension, diabetes mellitus, and other concomitant liver diseases were excluded from the NAFLD group. Echocardiograms of all groups were reviewed.

resultsSevere NAFLD compared to control was associated with a higher left ventricular mass after normalization for height

conclusionHealthy adults with NAFLD without metabolic syndrome, after adjusting for body mass index, demonstrated significant echocardiographic changes. Our results show that NAFLD is associated with preclinical cardiac disease, and this association is independent of traditional risk factors like systemic hypertension and diabetes mellitus.

Indexed as

diastolic dysfunctionechocardiogrammetabolic syndromeNonalcoholic fatty liver diseasepreclinical cardiac disease

Identifiers

PMID31763058
PMCPMC6872463
OpenAlexW2997023982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.