Evidence map›Paper›PMID 31762536›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2019

Deep learning-based stenosis quantification from coronary CT Angiography.

Youngtaek Hong, Frederic Commandeur, Sebastien Cadet, Markus Goeller, Mhairi K Doris, Xi Chen, Jacek Kwiecinski, Daniel S Berman, Piotr J Slomka, Hyuk-Jae Chang and 1 more

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  4. AI-Driven multi-view learning from CCTA for myocardial infarction diagnosis.The international journal of cardiovascular imaging · 2026
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  7. The role of artificial intelligence in coronary CT angiography.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Youngtaek HongBrain Korea 21 Project for Medical Science, Yonsei University, Seoul, Republic of Korea.
Frederic CommandeurBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Sebastien CadetDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Markus GoellerBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Mhairi K DorisDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Xi ChenDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Jacek KwiecinskiDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Daniel S BermanDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Piotr J SlomkaDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Hyuk-Jae ChangDepartment of internal medicine, Division of Cardiology, Severance Cardiovascular Hosp, Yonsei University College of Medicine, Seoul, Korea, Republic of.
Damini DeyBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Funding

Automated quantitative CT imaging of epicardial adipose tissue and risk of cardiac eventsR01HL133616 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI DEY, DAMINI · 2016 to 2019
$2.6M
NHLBI NIH HHS R01 HL133616
6 · The paper itself

Abstract

backgroundCoronary computed tomography angiography (CTA) allows quantification of stenosis. However, such quantitative analysis is not part of clinical routine. We evaluated the feasibility of utilizing deep learning for quantifying coronary artery disease from CTA.

methodsA total of 716 diseased segments in 156 patients (66 ± 10 years) who underwent CTA were analyzed. Minimal luminal area (MLA), percent diameter stenosis (DS), and percent contrast density difference (CDD) were measured using semi-automated software (Autoplaque) by an expert reader. Using the expert annotations, deep learning was performed with convolutional neural networks using 10-fold cross-validation to segment CTA lumen and calcified plaque. MLA, DS and CDD computed using deep-learning-based approach was compared to expert reader measurements.

resultsThere was excellent correlation between the expert reader and deep learning for all quantitative measures (r=0.984 for MLA; r=0.957 for DS; and r=0.975 for CDD, p<0.001 for all). The expert reader and deep learning method was not significantly different for MLA (median 4.3 mm

conclusionsOur deep learning-based method allows quantitative measurement of coronary artery disease segments accurately from CTA and may enhance clinical reporting.

Identifiers

PMID31762536
PMCPMC6874408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.