Evidence map›Paper›PMID 31762534›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2019

Coronary Calcium Detection using 3D Attention Identical Dual Deep Network Based on Weakly Supervised Learning.

Yuankai Huo, James G Terry, Jiachen Wang, Vishwesh Nath, Camilo Bermudez, Shunxing Bao, Prasanna Parvathaneni, J Jeffery Carr, Bennett A Landman

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuankai HuoDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, USA.
James G TerryDepartments of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, USA.
Jiachen WangDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, USA.
Vishwesh NathDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, USA.
Camilo BermudezDepartment of Biomedical Engineering, Vanderbilt University, Nashville, USA.
Shunxing BaoDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, USA.
Prasanna ParvathaneniDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, USA.
J Jeffery CarrDepartments of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, USA.
Bennett A LandmanDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, USA.
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Controlling Quality and Capturing Uncertainty in Advanced Diffusion Weighted MRIR01EB017230 · NIBIB · VANDERBILT UNIVERSITY · PI LANDMAN, BENNETT A. · 2015 to 2024
$5.1M
An Interactive Web-Based Game for Collaborative Labeling of Medical ImagesR21NS064534 · NINDS · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2009 to 2010
$436k
Quantitative Image Analysis Techniques for Optic Nerve DiseaseR21EY024036 · NEI · VANDERBILT UNIVERSITY · PI LANDMAN, BENNETT A. · 2014 to 2015
$410k
Resource Development for the Java Image Science ToolkitR03EB012461 · NIBIB · VANDERBILT UNIVERSITY · PI LANDMAN, BENNETT A. · 2010 to 2010
$147k
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR024975NEI NIH HHS R21 EY024036NIBIB NIH HHS R01 EB017230NIBIB NIH HHS R03 EB012461NINDS NIH HHS R21 NS064534
6 · The paper itself

Abstract

Coronary artery calcium (CAC) is biomarker of advanced subclinical coronary artery disease and predicts myocardial infarction and death prior to age 60 years. The slice-wise manual delineation has been regarded as the gold standard of coronary calcium detection. However, manual efforts are time and resource consuming and even impracticable to be applied on large-scale cohorts. In this paper, we propose the attention identical dual network (AID-Net) to perform CAC detection using scan-rescan longitudinal non-contrast CT scans with weakly supervised attention by only using per scan level labels. To leverage the performance, 3D attention mechanisms were integrated into the AID-Net to provide complementary information for classification tasks. Moreover, the 3D Gradient-weighted Class Activation Mapping (Grad-CAM) was also proposed at the testing stage to interpret the behaviors of the deep neural network. 5075 non-contrast chest CT scans were used as training, validation and testing datasets. Baseline performance was assessed on the same cohort. From the results, the proposed AID-Net achieved the superior performance on classification accuracy (0.9272) and AUC (0.9627).

Indexed as

3D grad-camAID-NetattentionCACcoronary artery calcium

Identifiers

PMID31762534
PMCPMC6874228
OpenAlexW2899743512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.