Evidence map›Paper›PMID 31762222›Full record

ArticleOrthopaedic surgery2019

Comparison of the Effects of Proximal Humeral Internal Locking System (PHILOS) Alone and PHILOS Combined with Fibular Allograft in the Treatment of Neer Three- or Four-part Proximal Humerus Fractures in the Elderly.

Lei Zhao, Yi-Min Qi, Lei Yang, Gang-Rui Wang, Sheng-Nai Zheng, Qiang Wang, Bin Liang, Chun-Zhi Jiang

Open access · goldAbstract readComparative Study
In one paragraph

Article in Orthopaedic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 6 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 6 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. The effects of augmentation choices for locking plate fixation in proximal humerus fracture osteosynthesis: a systematic review and meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
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  6. Interventions for treating proximal humeral fractures in adults.The Cochrane database of systematic reviews · 2022
    Pooled it
  7. Influence of allograft augmentation on surgical outcomes and complications in proximal humerus fractures: a matched-pair analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  8. Article
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  10. Proximal humerus fractures in the elderly: is there (still) a role for plate osteosynthesis?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Review
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  12. Clinico-radiological outcomes of four-part proximal humerus fracture fixation with fibular strut graft augmentation.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lei ZhaoDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0001-9440-3561
Yi-Min QiDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Lei YangDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Gang-Rui WangDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Sheng-Nai ZhengDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Qiang WangDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Bin LiangDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Chun-Zhi JiangDepartment of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare and analyze the clinical outcomes of the proximal humeral internal locking system (PHILOS) alone and the PHILOS combined with fibular allograft in the treatment of Neer three- and four-part proximal humerus fractures (PHF) in the elderly.

methodsFrom January 2014 to January 2018, a total of 42 elderly patients with Neer three- or four-part PHF admitted to our hospital were randomly divided into observation group and control group, with 21 patients in each group. The observation group was treated with the PHILOS combined with fibular allograft. The control group was treated with the PHILOS alone. Perioperative parameters and fracture classification were recorded in the two groups. Function results were assessed by Visual Analog Scale (VAS), Constant-Murley score (CMS), American Shoulder and Elbow Surgeons (ASES) score, and the Disability of Arm-Shoulder-Hand (DASH) score. Radiological results were evaluated using the neck-shaft angle (NSA) and humeral head height (HHH), and complications were also recorded in each group.

resultsThere were no significant differences between the two groups in terms of preoperative status, age, gender, cause of trauma, fracture site, and fracture classification. The average follow-up time was 12 months. At the last follow-up, the VAS and DASH observation groups were lower than the control group, and there was significant difference between the two groups (P < 0.05). The CMS and ASES were higher in the observation group than the control group, and there was significant difference between the two groups (P < 0.05). The mean difference in the NSA and HHH were lower in the observation group than the control group, and there was a significant difference between the two groups (P < 0.05). There was one postoperative complication in the observation group, which was humeral head avascular necrosis (AVN). There were seven postoperative complications in the control group, including three cases of humeral head collapse and three cases of screw cutout and one case of humeral head AVN. The incidence of postoperative complications in the observation group was significantly lower than the control group (P < 0.05), there was a significant difference between the two groups.

conclusionsFor Neer three- or four-part PHF in the elderly patients, PHILOS fixation with fibular allograft shows satisfactory short-term results with respect to humeral head support and maintenance of reduction, and may reduce the incidence of complications associated with fixation using a PHILOS alone.

Indexed as

AgedAllograftsDisability EvaluationFemaleFibulaFracture Fixation, InternalHumansMaleMiddle AgedPain MeasurementRadiographyRange of Motion, ArticularRetrospective StudiesShoulder FracturesTreatment OutcomeAnatomical allograftElderlyFibular shaftProximal humeral internal locking systemProximal humerus fractures

Identifiers

PMID31762222
PMCPMC6904636
OpenAlexW2991169034

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.