Evidence map›Paper›PMID 31762121›Full record

ArticleNMR in biomedicine2020

Combined endogenous MR biomarkers to assess changes in tumor oxygenation induced by an allosteric effector of hemoglobin.

Thanh-Trang Cao-Pham, An Tran-Ly-Binh, Arne Heyerick, Catherine Fillée, Nicolas Joudiou, Bernard Gallez, Bénédicte F Jordan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Thanh-Trang Cao-PhamLouvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.
An Tran-Ly-BinhLouvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.
Arne HeyerickNormoxys Inc., Boston, Massachusetts.
Catherine FilléeInstitut de Recherche Expérimentale et Clinique (IREC), UCLouvain, Universite catholique de Louvain, Brussels, Belgium.
Nicolas JoudiouLouvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.
Bernard GallezLouvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.ORCID 0000-0002-5708-1302
Bénédicte F JordanLouvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.ORCID 0000-0002-7126-2206
UCLouvain · BEAcXys Technologies (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia is a crucial factor in cancer therapy, determining prognosis and the effectiveness of treatment. Although efforts are being made to develop methods for assessing tumor hypoxia, no markers of hypoxia are currently used in routine clinical practice. Recently, we showed that the combined endogenous MR biomarkers, R

Indexed as

Magnetic Resonance SpectroscopyAllosteric RegulationAnimalsBiomarkers, TumorCell Line, TumorGliomaHemoglobinsInositol PhosphatesNeoplasmsOxygenOxygen ConsumptionRatsRhabdomyosarcomaBiomarkers, TumorHemoglobinsInositol Phosphatesinositol trispyrophosphateOxygenmagnetic resonance imagingmyo-inositol trispyrophosphate∆R1, ∆R2*, tumor hypoxia

Identifiers

PMID31762121
PMCPMC7003919
OpenAlexW2990344386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.