Evidence map›Paper›PMID 31761883›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Importance and Difficulty of Differentiating BMA-induced AFF Prodromal Symptoms from Hormonal Therapy-related Femoral Pain.

Shuji Ota, Toru Tokizaki, Masakazu Sugimoto, Ryosuke Ochiai, Terunobu Haruyama, Masashi Ishihara, Maika Natsume, Yoko Fukasawa, Takahiko Sakamoto, Shigeru Tanzawa and 6 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Shuji OtaDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Toru TokizakiDepartment of Orthopaedic Surgery, Teikyo University School of Medicine, Japan.
Masakazu SugimotoDepartment of Pharmacy, Teikyo University Hospital, Japan.
Ryosuke OchiaiDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Terunobu HaruyamaDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Masashi IshiharaDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Maika NatsumeDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoko FukasawaDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Takahiko SakamotoDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Shigeru TanzawaDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Ryo UsuiDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Takeshi HondaDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Yasuko IchikawaDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Kiyotaka WatanabeDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Hirotaka KawanoDepartment of Orthopaedic Surgery, Teikyo University School of Medicine, Japan.
Nobuhiko SekiDivision of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Japan.
Teikyo University · JPTeikyo University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of breast cancer in a 74-year-old woman treated with exemestane as fourth-line hormonal therapy and bone-modifying agents for long time. She suddenly developed a right femoral shaft fracture during treatment. Her femoral fracture had a beaking sign on radiogram. Given this finding, her fracture was ultimately diagnosed as atypical femoral fracture (AFF). In this case, it was difficult to recognize the difference between groin pain as a prodromal symptom of AFF and that due to an adverse reaction to hormonal therapy. Therefore, clinicians should recognize the difficulty of this differentiation and consider the situation with caution.

Indexed as

Prodromal SymptomsAgedBone Density Conservation AgentsBreast NeoplasmsFemaleFemoral FracturesHumansPainBone Density Conservation Agentsatypical femoral fracturebone-modifying agentsbreast cancerhormone therapy

Identifiers

PMID31761883
PMCPMC7118384
OpenAlexW2989692244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.