Evidence map›Paper›PMID 31760772›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Developmental changes in the utilization of citrulline by neonatal pigs.

Mahmoud A Mohammad, Inka C Didelija, Xioying Wang, Barbara Stoll, Douglas G Burrin, Juan C Marini

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. L-Citrulline in Neonates: From Bench to Bed Side.Children (Basel, Switzerland) · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Mahmoud A MohammadUnited States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas.
Inka C DidelijaUnited States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas.
Xioying WangUnited States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas.
Barbara StollUnited States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas.
Douglas G BurrinUnited States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-8792-3339
Juan C MariniUnited States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-1810-4479
Agricultural Research Service · US

Funding

Therapeutic and Metabolic Responses of Citrulline vs. Arginine SupplementationR01GM108940 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BURRIN, DOUGLAS G · 2014 to 2023
$2.2M
NIGMS NIH HHS R01 GM108940
6 · The paper itself

Abstract

Developmental changes in the renal expression and activity of argininosuccinate synthase (ASS1) and argininosuccinate lyase (ASL), enzymes that use citrulline for the production of arginine, have been reported. Thus, the ability of neonates, and especially premature neonates, to produce arginine may be compromised. To determine the utilization of citrulline in vivo, we measured renal expression of

Indexed as

AgingAnimalsAnimals, NewbornArginineCitrullineFemaleKidneyMaleSwineArginineCitrullineargininecitrullinekineticsneonatalpremature

Identifiers

PMID31760772
PMCPMC6985816
OpenAlexW2990153683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.