Evidence map›Paper›PMID 31760766›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2020

Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras.

Kinji Asahina, Steven Balog, Edward Hwang, Eugene Moon, Emily Wan, Kaitlin Skrypek, Yibu Chen, Jay Fernandez, Janet Romo, Qihong Yang and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Inactivation of HIPK2 attenuates KRASJournal of experimental & clinical cancer research : CR · 2024
    Article
  4. The role of autophagy in pancreatic diseases.Frontiers in pharmacology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. A review of physical activity in pancreatic ductal adenocarcinoma: Epidemiology, intervention, animal models, and clinical trials.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2022
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Kinji AsahinaThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0000-0003-0398-8395
Steven BalogThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Edward HwangThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Eugene MoonThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Emily WanThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Kaitlin SkrypekThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Yibu ChenBioinformatics Service, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Jay FernandezThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Janet RomoThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Qihong YangThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Keane LaiThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Samuel W FrenchHarbor-Univeristy of California, Los Angeles, Medical Center, Torrance, California.
Hidekazu TsukamotoThe Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.
University of Southern California · USUCLA Medical Center · US

Funding

The Southernearch Center for ALPD and CirrhosisP50AA011999 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIDEKAZU TSUKAMOTO · 1999 to 2026
$45.8M
Stearoyl-CoA Desaturase in Alcohol-Promoted Liver TumorigenesisK08AA025112 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LAI, KEANE · 2017 to 2021
$978k
NIAAA NIH HHS K08 AA025112NIAAA NIH HHS P50 AA011999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alcohol DrinkingAnimalsCarcinogensCarcinoma, Pancreatic DuctalCentral Nervous System DepressantsCeruletideCytokinesDiet, WesternEthanolHepatocytesHomeodomain ProteinsLiver NeoplasmsMiceMutationNicotinePancreatic NeoplasmsCarcinogensCentral Nervous System DepressantsCeruletideCytokinesEthanolHomeodomain ProteinsHras protein, mouseNicotinepancreatic and duodenal homeobox 1 proteinProto-Oncogene Proteins p21(ras)Trans-Activatorsacinar-ductal metaplasiametastasisnephronectinpancreatic intraepithelial neoplasia

Identifiers

PMID31760766
PMCPMC7052574
OpenAlexW2991533479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.