Evidence map›Paper›PMID 31760764›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2020

Absorptive transport of amino acids by the rat colon.

Yuxin Chen, Meredith M Dinges, Andrew Green, Scott E Cramer, Cynthia K Larive, Christian Lytle

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Effects ofNutrients · 2026
    Trial
  2. Article
  3. Article
  4. Review
  5. ACE2: Friend or Foe in Post-COVID-19 Neurodegeneration?International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Tryptophan-synthesizing bacteria enhance colonic motility.Neurogastroenterology and motility · 2023
    Article
  10. Article
  11. Article
  12. Flux coupling, not specificity, shapes the transport and phylogeny of SLC6 glycine transporters.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. CaFrontiers in pharmacology · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuxin ChenDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, California.
Meredith M DingesDepartment of Chemistry, University of California, Riverside, California.
Andrew GreenDepartment of Chemistry, University of California, Riverside, California.
Scott E CramerDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, California.
Cynthia K LariveDepartment of Chemistry, University of California, Riverside, California.
Christian LytleDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, California.
University of California, Riverside · US

Funding

Delineating Intestinally Absorbed (Bioavailable) Microbial Metabolites by Metabolomic ProfilingR21DK110516 · NIDDK · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI LYTLE, CHRISTIAN Y · 2017 to 2018
$402k
NIDDK NIH HHS R21 DK110516
6 · The paper itself

Abstract

The capacity of the colon to absorb microbially produced amino acids (AAs) and the underlying mechanisms of AA transport are incompletely defined. We measured the profile of 16 fecal AAs along the rat ceco-colonic axis and compared unidirectional absorptive AA fluxes across mucosal tissues isolated from the rat jejunum, cecum, and proximal colon using an Ussing chamber approach, in conjunction with

Indexed as

Intestinal AbsorptionAmino AcidsAmino Acid Transport SystemsAnimalsBacteriaColonFecesFemaleGastrointestinal MicrobiomeIntestinal MucosaKineticsRats, Sprague-DawleyTranscriptomeAmino AcidsAmino Acid Transport Systemsamino acidcecumcolonLC-MSmetabolomeNMRtransporterUssing chamber

Identifiers

PMID31760764
PMCPMC6985843
OpenAlexW2991077943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.