ReviewKorean circulation journal2019
Understanding Vulnerable Plaques: Current Status and Future Directions.
Review in Korean circulation journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Association between in-stent neointimal characteristics and native coronary artery disease progression.PloS one · 2021Trial
- Advancing Coronary Risk Assessment Through Combined Radiomic, Mechanical, and Hemodynamic Analysis.Annals of biomedical engineering · 2026Article
- Intracoronary Imaging for the Management of Vulnerable Plaques.Journal of clinical medicine · 2026Review
- Study on the association between neovascularization of culprit lesions and plaque rupture in patients with acute myocardial infarction.BMC cardiovascular disorders · 2025Article
- NINJ1 and MMP9: potential biomarkers for intracranial atherosclerosis plaque vulnerability.Frontiers in neurology · 2025Article
- Therapeutic Potential of Targeting p27Archives of internal medicine research · 2024Article
- Coronary Physiology-Based Approaches for Plaque Vulnerability: Implications for Risk Prediction and Treatment Strategies.Korean circulation journal · 2023Review
- Review
- SFRP4 Reduces Atherosclerosis Plaque Formation in ApoE Deficient Mice.Cardiology research and practice · 2023Article
- Vulnerable Atherosclerotic Plaque: Is There a Molecular Signature?International journal of molecular sciences · 2022Review
- Detecting vulnerable carotid plaque and its component characteristics: Progress in related imaging techniques.Frontiers in neurology · 2022Review
- Molecular Imaging of Vulnerable Coronary Plaque with Radiolabeled Somatostatin Receptors (SSTR).Journal of clinical medicine · 2021Review
- Role of Inflammation in Arterial Calcification.Korean circulation journal · 2021Review
- Application of targeted therapy strategies with nanomedicine delivery for atherosclerosis.Acta pharmacologica Sinica · 2021Review
- Establishment of a Novel Mouse Model for Atherosclerotic Vulnerable Plaque.Frontiers in cardiovascular medicine · 2021Article
- Review
- The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability.Mediators of inflammation · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The main cause of acute myocardial infarction is plaque rupture accompanied by superimposed coronary thrombosis. Thin-cap fibroatheromas (TCFAs) have been suggested as a type of lesion with a vulnerability that can cause plaque rupture. However, not only the existence of a TCFA but also the fine and complex interactions of other anatomical and hemodynamic factors, such as microcalcification in the fibrous cap, cholesterol crystal-induced inflammasome activation, the apoptosis of intraplaque macrophages, and endothelial shear stress distribution should precede a clinical event caused by plaque rupture. Recent studies are being conducted to identify these mechanisms through molecular imaging and hemodynamic assessment using computational fluid dynamics, which will result in better clinical results through selective coronary interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.