Evidence map›Paper›PMID 31760561›Full record

ArticleMolecular diversity2020

Modeling antimalarial and antihuman African trypanosomiasis compounds: a ligand- and structure-based approaches.

Jyoti Gahtori, Suyash Pant, Hemant Kumar Srivastava

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular diversity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Pyrazolo[4,3-International journal of molecular sciences · 2023
    Article
  2. Article
  3. Article
  4. Article
  5. Inhibition of the RNA-dependent RNA Polymerase of the SARS-CoV-2 by Short Peptide Inhibitors.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2021
    Article
  6. Article
  7. Article
  8. Peptide-like and small-molecule inhibitors against Covid-19.Journal of biomolecular structure & dynamics · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jyoti GahtoriDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India.
Suyash PantDepartment of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research Kolkata, Kolkata, WB, 700032, India.
Hemant Kumar SrivastavaDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India. hemantkrsri@gmail.com.ORCID http://orcid.org/0000-0001-6589-6854

Funding

Science and Engineering Research Board SB/S2/RJN/004-2015
6 · The paper itself

Abstract

This study examines the interaction of 137 antimalarial and antihuman African trypanosomiasis compounds [bis(2-aminoimidazolines), bisguanidinediphenyls and polyamines] on three different in vitro assays (Trypanosoma brucei rhodesiense (T.b.r.), Plasmodium falciparum (P.f.) and cytotoxicity-L6 cells). ΔT

Indexed as

AnimalsAntimalarialsLigandsMolecular Docking SimulationPlasmodium falciparumQuantitative Structure-Activity RelationshipTrypanosomiasis, AfricanAntimalarialsLigandsCytotoxicity-L6DockingMD simulationPlasmodium falciparumQSARTrypanosoma brucei rhodesiense

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.