Evidence map›Paper›PMID 31760550›Full record

ArticleBehavior genetics2020

Pathways Between a Polygenic Score for Educational Attainment and Higher Educational Attainment in an African American Sample.

Jill A Rabinowitz, Sally I-Chun Kuo, Benjamin Domingue, Mieka Smart, William Felder, Kelly Benke, Brion S Maher, Nicholas S Ialongo, George Uhl

Open access · greenAbstract read
In one paragraph

Article in Behavior genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Genetics and Socioeconomic Status: Some Preliminary Evidence on Mechanisms.Journal of political economy microeconomics · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jill A RabinowitzDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Heath, Baltimore, USA. jrabino3@jhu.edu.ORCID 0000-0002-3674-8032
Sally I-Chun KuoDepartment of Psychology, Virginia Commonwealth University, Richmond, USA.
Benjamin DomingueDepartment of Sociology, Stanford University, Stanford, USA.
Mieka SmartCollege of Human Medicine, Michigan State University, East Lansing, USA.
William FelderDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Heath, Baltimore, USA.
Kelly BenkeDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Heath, Baltimore, USA.
Brion S MaherDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Heath, Baltimore, USA.
Nicholas S IalongoDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Heath, Baltimore, USA.
George UhlNew Mexico VA Health Care System, Las Vegas, USA.
Johns Hopkins University · USMichigan State University · USNew Mexico VA Health Care System · USStanford University · USVirginia Commonwealth University · US

Funding

PERIODIC FOLLOW UP OF TWO UNIVERSAL PREVENTIVE TRIALSR01MH057005 · NIMH · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 1998 to 2007
$4.2M
Development & Malleability from Childhood to AdulthoodR01DA044184 · NIDA · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 2018 to 2022
$3.9M
NIDA NIH HHS R01 DA044184NIMH NIH HHS R01 MH057005
6 · The paper itself

Abstract

We investigated the extent to which performance on standardized achievement tests, executive function (EF), and aggression in childhood and adolescence accounted for the relationship between a polygenic score for educational attainment (EA PGS) and years of education in a community sample of African Americans. Participants (N = 402; 49.9% female) were initially recruited for an elementary school-based prevention trial in a Mid-Atlantic city and followed into adulthood. In first and twelfth grade, participants completed math and reading standardized tests and teachers reported on participants' aggression and EF, specifically impulsivity and concentration problems. At age 20, participants reported on their years of education and post-secondary degrees attained and their genotype was assayed from blood or buccal swabs. An EA PGS was created using results from a large-scale GWAS on EA. A higher EA PGS was associated with higher education indirectly via adolescent achievement. No other mediating mechanisms were significant. Adolescent academic achievement is thus one mechanism through which polygenic propensity for EA influences post-secondary education among urban, African American youth.

Indexed as

Academic PerformanceAcademic SuccessAdolescentAdultAdverse Childhood ExperiencesAggressionBlack or African AmericanChildChild, PreschoolEducational StatusExecutive FunctionFemaleGenotypeHumansLongitudinal StudiesMaleAchievementAdolescenceAggressionChildhoodEducational attainmentExecutive functionPolygenic score

Identifiers

PMID31760550
PMCPMC6942631
OpenAlexW2990817579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.